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Hepatitis E outbreaks are a serious public health concern in developing countries. The disease causes acute infections, primarily in young adults. The mortality rate is approximately 2%; however, it can exceed 20% in pregnant women in some regions in India. The causative agent, hepatitis E virus (HEV), has been isolated from several animal species, including pigs. HEV genotypes 3 and 4 have been isolated from both humans and animals, and are recognized as zoonotic pathogens. Seroprevalence studies in animals and humans indirectly suggest that HEV infections occur worldwide. The virus is primarily transmitted to humans via undercooked animal meats in developed countries. Moreover, transfusion- and transplantation-mediated HEV infections have recently been reported. This review summarizes the general characteristics of hepatitis E, HEV infection status in animals and humans, the zoonotic transmission modes of HEV, and HEV vaccine development status.
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광주지역 도축 돼지 및 가공품 E형 간염 실태 조사
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First report of cross-species transmission of deer hepatitis E virus to a guanaco in Korea
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A Survey on the Status of Hepatitis E Virus Infection Among Slaughterhouse Workers in South Korea
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Detection and genetic analysis of zoonotic hepatitis E virus, rotavirus, and sapovirus in pigs
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Epidemiological Aspects of Hepatitis E Virus Infections between South Korea and Japan
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Extrahepatic manifestations of hepatitis E virus: An overview
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Association of Hepatitis B Virus Infection and Psoriasis
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