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자료유형
학술저널
저자정보
Hansol Yeom (Division of Infectious Disease Response Capital Regional Center for Disease Control and Prevention Seoul Korea) Soonryu Seo (Division of Infectious Disease Control Bureau of Infectious Disease Policy Korea Disease Control and Prevention Agency Cheongju Korea) Youngsil Yoon (Division of Infectious Disease Control Bureau of Infectious Disease Policy Korea Disease Control and Prevention Agency Cheongju Korea) Jaeeun Lee (Division of Immunization Bureau of Healthcare Safety and Immunization Korea Disease Control and Prevention Agency Cheongju Korea) Myung-Guk Han (Division of Viral Disease Bureau of Infectious Disease Diagnosis Control Korea Disease Control and Prevention Agency Cheongju Korea) Lee Deog-Yong (Division of Viral Diseases Center for Laboratory Control of Infectious Diseases Korea Centers for Disease Control and Prevention Osong Korea.) Sun-Whan Park (Division of Viral Disease Bureau of Infectious Disease Diagnosis Control Korea Disease Control and Prevention Agency Cheongju Korea) Song A Park (Division of Viral Disease Bureau of Infectious Disease Diagnosis Control Korea Disease Control and Prevention Agency Cheongju Korea) Jeong Sook-Hyang (Department of Internal Medicine Seoul National University Bundang Hospital Seoul National University College of Medicine Seongnam Korea) Jin Gwack (Division of Infectious Disease Control Bureau of Infectious Disease Policy Korea Disease Control and Prevention Agency Cheongju Korea)
저널정보
질병관리본부 Osong Public Health and Research Persptectives Osong Public Health and Research Perspectives 제14권 제1호
발행연도
2023.2
수록면
15 - 22 (8page)
DOI
10.24171/j.phrp.2022.0305

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Objectives: On February 16, 2022, 12 cases of hepatitis E virus (HEV) infection were reported in a food manufacturing factory in Korea. The aim of this study was to identify additional cases and to determine the source of this HEV outbreak. Methods: This study was an in-depth investigation of 12 HEV immunoglobulin M (IgM)-positive cases and their demographic, clinical, and epidemiological characteristics. On-site specimens were collected from the environment and from humans, and a follow-up investigation was conducted 2 to 3 months after the outbreak. Results: Among 80 production workers in the factory, 12 (15.0%) had acute HEV infection, all of whom were asymptomatic. The follow-up investigation showed that 3 cases were HEV IgM-positive, while 6 were HEV IgG-positive. HEV genes were not detected in the HEV IgM-positive specimens. HEV genes were not detected in the food products or environmental specimens collected on-site. HEV was presumed to be the causative pathogen. However, it could not be confirmed that the source of infection was common consumption inside the factory. Conclusion: This was the first domestic case of an HEV infection outbreak in a food manufacturing factory in Korea. Our results provide information for the future control of outbreaks and for the preparation of measures to prevent domestic outbreaks of HEV infection.

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