지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 717 - 740 (24page)
- DOI
- 10.1007/s11816-021-00711-3
이용수
초록· 키워드
오류제보하기
Isoflavones (ISF) are potent secondary metabolites, widely distributed among the members of the Fabaceae family. They have a multitude of biological functions in plants, animals, and humans. Most of the functions exhibited by isoflavones are highly beneficial to human beings. Benefits mainly include lowering cardiovascular diseases, reducing menopausal symptoms, and decreasing the risk of hormone-related cancers. Therefore, this potent compound has emerged as a promising possibility for making medicines and has grabbed the pharmaceutical industry's attention. Nowadays, many isoflavone-based products are manufactured commercially as food supplements, and their demand is drastically increasing globally. Numerous?in vitro?stud- ies have successfully synthesized value-added metabolites that possess a vast number of industrial applications. Production of isoflavones within the plants depends on several biological and environmental conditions. Hence,?in vitro?cultures pro- vide an alternate source to recover these compounds independent of environmental factors and limited bio-resources. Plant organ cultures could be highly recommended as a reliable platform for synthesizing plant-based pharmaceutically active isoflavones. Moreover, biotechnological approaches, such as elicitation and precursor feeding, can eventually promote the yield and increase these metabolites' production. This review initially outlines information regarding the source, structure, synthesis, and diverse roles of isoflavones. Later, this paper describes different plant organ cultures for the?in vitro?production of isoflavones and highlights elicitation strategies as well as metabolic engineering work to enhance production.
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등록된 정보가 없습니다.
참고문헌 (184)
참고문헌 신청
Adler SA / 2015 / Phytoestrogens and their metabolites in bulk-tank milk: effects of farm management and season / PLoS ONE 10:e0127187
Akashi T / 2005 / Isoflavonoid production by adventitious-root cultures of Iris germanica (Iridaceae) / Plant Biotechnol 22:207~215
Algar E / 2012 / Pseudomonas fluorescens N21.4 metabolites enhance secondary metabolism isoflavones in soybean (Glycine max) calli cultures / J Agric Food Chem 60:11080~11087
Al-Tawaha AM / 2005 / Biotic elicitors as a means of increasing isoflavone concentration of soybean seeds / Ann Appl Biol 146:303~310
Ames TT / 1997 / Continuous production of daidzein and genistein from soybean in a magnetofluidized bed bioreactor / Biotechnol Prog 13:336~339
Akashi T / 2005 / Isoflavonoid production by adventitious-root cultures of Iris germanica (Iridaceae) / Plant Biotechnol 22:207~215
Algar E / 2012 / Pseudomonas fluorescens N21.4 metabolites enhance secondary metabolism isoflavones in soybean (Glycine max) calli cultures / J Agric Food Chem 60:11080~11087
Al-Tawaha AM / 2005 / Biotic elicitors as a means of increasing isoflavone concentration of soybean seeds / Ann Appl Biol 146:303~310
Ames TT / 1997 / Continuous production of daidzein and genistein from soybean in a magnetofluidized bed bioreactor / Biotechnol Prog 13:336~339
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