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자료유형
학술저널
저자정보
Byeonggwan Noh (Division of Hepato-Biliary-Pancreatic Surgery and Transplantation Department of Surgery Pusan Natio) Lee Nuri (Division of Hepato-Biliary-Pancreatic Surgery and Transplantation Veterans Health Service Medical C) Lee Jae Il (Department of Neurosurgery Biomedical Research Institute Pusan National University Hospital Busan K) 윤명희 (부산대학교)
저널정보
대한이식학회 Clinical Transplantation and Research Korean Journal of Transplantation Vol.35 No.4
발행연도
2021.12
수록면
275 - 280 (6page)
DOI
10.4285/kjt.21.0021

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Intracranial hemorrhage (ICH) following liver transplantation is a potentially devastating complication. Although hypertension and thrombocytopenia are well-known risk factors for ICH in the general population, their roles in ICH after liver transplantation have not been well established. ICH occurred in two patients with alcoholic cirrhosis after deceased donor liver transplantation. A 38-year-old man presented with acute ICH in the right parietal lobe on day 16 after transplantation, with decreased level of consciousness and seizure. His mental status improved with immediate neurological treatment without surgery. In the second case, a 42-year-old woman had acute ICH in the left frontoparietal lobes on day 9 after transplantation, with generalized tonic-clonic seizures. Urgent cerebral decompression was performed. The patient’s neurological symptoms gradually recovered. In both cases, the blood platelet count was less than 50,000/mm3. Monitoring cerebral pressure for ICH is an invasive and challenging method, especially in patients with cirrhosis who have issues with hemostasis. Surgeons should be critically mindful of the risk of rapid neurological deterioration in patients with cirrhosis. Careful neurologic examination and immediate treatment to lower intracranial pressure for ICH after liver transplantation in patients with alcoholic cirrhosis are very important.

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