지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한응급의학회 Clinical and Experimental Emergency Medicine Clinical and Experimental Emergency Medicine Vol.8 No.3
- 발행연도
- 2021.9
- 수록면
- 173 - 181 (9page)
- DOI
- https://doi.org/10.15441/ceem.20.094
이용수
초록· 키워드
오류제보하기
Objective Although fluid resuscitation is the cornerstone of treatment for sepsis, the role of body water status in sepsis is poorly understood. This study aimed to understand how body water and its distribution are modified in patients with sepsis and those with non-septic infection compared to healthy individuals. Methods Two groups of adults presumed to have non-septic infection (n=87) and sepsis (n=54) were enrolled in this prospective study in a single emergency department, and they were compared to sex-, age-, and height-matched (1:3 ratio) healthy controls (n=11,190) from retrospective data in a health promotion center. Total body water (TBW), intracellular water (ICW), and extracellular water (ECW), determined using direct segmental multi-frequent bioelectrical impedance analysis (InBody S10) were expressed as indices for normalization by body weight (BW). The ratio of ECW to TBW (ECW/TBW) was evaluated to determine body water distribution. Results TBW/BW, ICW/BW, and ECW/BW were significantly higher in the non-septic infection group than in the healthy group (P<0.001), but ECW/TBW was not significantly different (P=0.690). There were no differences in TBW/BW and ICW/BW between the sepsis and healthy groups (P=0.083 and P=0.963). However, ECW/BW and ECW/TBW were significantly higher in the sepsis group than in the healthy group (P<0.001). Conclusion Compared to the healthy group, the ratio of body water to BW was significantly increased in the non-septic infection group, while ECW/BW and ECW/TBW were significantly increased in the sepsis group. These indices could be utilized as diagnostic variables of body water deficit in septic patients.
목차
등록된 정보가 없습니다.
참고문헌 (46)
참고문헌 신청
Rhodes A / 2017 / Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock. 2016 / Crit Care Med 45:486~552
ProCESS Investigators / 2014 / A randomized trial of protocol-based care for early septic shock / N Engl J Med 370:1683~1693
ARISE Investigators / 2014 / Goal-directed resuscitation for patients with early septic shock / N Engl J Med 371:1496~1506
Levy MM / 2018 / The Surviving Sepsis Campaign Bundle : 2018 update / Intensive Care Med 44:925~928
Marik P / 2016 / A rational approach to fluid therapy in sepsis / Br J Anaesth 116:339~349
ProCESS Investigators / 2014 / A randomized trial of protocol-based care for early septic shock / N Engl J Med 370:1683~1693
ARISE Investigators / 2014 / Goal-directed resuscitation for patients with early septic shock / N Engl J Med 371:1496~1506
Levy MM / 2018 / The Surviving Sepsis Campaign Bundle : 2018 update / Intensive Care Med 44:925~928
Marik P / 2016 / A rational approach to fluid therapy in sepsis / Br J Anaesth 116:339~349
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