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논문 기본 정보

자료유형
학술저널
저자정보
Kim Minhye (Department of Pediatrics Seoul National University Bundang Hospital Seongnam Seoul National Univers) Choi Sujin (Department of Pediatrics Seoul National University Bundang Hospital Seongnam Seoul National Univers) Jung Young Hwa (Department of Pediatrics Seoul National University Bundang Hospital Seongnam Seoul National Univers) Choi Chang Won (Department of Pediatrics Seoul National University Bundang Hospital Seongnam Seoul National Univers) Shin Myoung-jin (Infection Control Center Seoul National University Bundang Hospital Seongnam the Republic of Korea.) Kim Eu Suk (Infection Control Center Seoul National University Bundang Hospital Seongnam the Republic of Korea.) Lee Hyunju (Department of Pediatrics Seoul National University Bundang Hospital Seongnam Seoul National Univers)
저널정보
대한소아감염학회 Pediatric Infection and Vaccine Pediatric Infection and Vaccine 제28권 제3호
발행연도
2021.12
수록면
133 - 143 (11page)
DOI
10.14776/piv.2021.28.e18

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Purpose: This study aimed to determine the incidence of central line-associated bloodstream infection (CLABSI) in the neonatal intensive care unit (NICU), evaluate the patients' clinical characteristics, and identify the etiologic agents for guidance in prevention and treatment. Methods: A retrospective chart review study of infants classified as having CLABSI was conducted at the NICU of Seoul National University Bundang Hospital from January 2016 to December 2020. Results: Of the 45 infants, 53 had CLABSIs within a follow-up period of 18,622 catheter days. The incidence of CLABSIs was 2.85 per 1,000 catheter days. The most common catheter type was a peripherally inserted central catheter (n=47, 81%). A total of 57 pathogens were isolated, of which 57.9% (n=33) were Gram-positive bacteria, 36.8% (n=21) were Gram-negative bacteria, and 5.3% (n=3) were Candida spp. The most common pathogens were Staphylococcus aureus (n=12, 21%) and coagulase-negative staphylococci (n=12, 21%), followed by Klebsiella aerogenes (n=8, 14%). The median duration of bacteremia was 2 days, and 19 episodes showed bacteremia for 3 days or more. The mortality rate of infants within 14 days of CLABSI was 13.3% (n=6). Conclusions: This study analyzed the incidence of CLABSI and the distribution of pathogens in the NICU. Continuous monitoring of CLABSI based on active surveillance serves as guidance for empiric antibiotic use and also serves as a tool to assess the necessity for implementation of prevention strategies and their impact.

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