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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 348 - 354 (7page)
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Purpose: Over the last 30 years, Serratia marcescens (S. marcescens) has emerged as an important pathogen, and a common cause of nosocomial infections. The aim of this study was to identify risk factors associated with mortality in patients with S. marcescens bacteremia. Materials and Methods: We performed a retrospective cohort study of 98 patients who had one or more blood cultures positive for S. marcescens between January 2006 and December 2012 in a tertiary care hospital in Seoul, South Korea. Multiple risk factors were compared with association with 28-day all-cause mortality. Results: The 28-day mortality was 22.4% (22/98 episodes).
In a univariate analysis, the onset of bacteremia during the intensive care unit stay (p=0.020), serum albumin level (p=0.011), serum C-reactive protein level (p=0.041), presence of indwelling urinary catheter (p=0.023), and Sequential Oran Failure Assessment (SOFA) score at the onset of bacteremia (p<0.001) were significantlydifferent between patients in the fatal and non-fatal groups. In a multivariateanalysis, lower serum albumin level and an elevated SOFA score were independentlyassociated with 28-day mortality [adjusted odds ratio (OR) 0.206, 95% confidential interval (CI) 0.044‒0.960, p=0.040, and adjusted OR 1.474, 95% CI 1.200‒1.810, p<0.001, respectively]. Conclusion: Lower serum albumin level and an elevated SOFA score were significantly associated with adverse outcomes in patients with S. marcescens bacteremia.
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참고문헌 (23)
참고문헌 신청
Bonnet R / 2000 / A novel class A extended-spectrum beta-lactamase (BES-1) in Serratia marcescens isolated in Brazil / Antimicrob Agents Chemother 44 : 3061 ~ 3068
Carratala J / 2003 / Factors associated with complications and mortality in adult patients hospitalized for infectious cellulitis / Eur J Clin Microbiol Infect Dis 22 : 151
Cheong HS / 2012 / Clinical significance of infections caused by extended-spectrum β-lactamase-producing Enterobacteriaceae blood isolates with inducible AmpC β-lactamase
Choi SH / 2002 / Serratia bacteremia in a large university hospital: trends in antibiotic resistance during 10 years and implications for antibiotic use / Infect Control Hos
Clinical and Lab
Carratala J / 2003 / Factors associated with complications and mortality in adult patients hospitalized for infectious cellulitis / Eur J Clin Microbiol Infect Dis 22 : 151
Cheong HS / 2012 / Clinical significance of infections caused by extended-spectrum β-lactamase-producing Enterobacteriaceae blood isolates with inducible AmpC β-lactamase
Choi SH / 2002 / Serratia bacteremia in a large university hospital: trends in antibiotic resistance during 10 years and implications for antibiotic use / Infect Control Hos
Clinical and Lab
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