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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.6
- 수록면
- 112 - 118 (7page)
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초록· 키워드
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Objectives: The Toxoplasma gondii (T. gondii) is an intracellular opportunistic protozoan parasite that infects approximately one-third of the human population worldwide. Honey has long been used for treatment of many diseases in folk medicine. Honey has exhibited significant anthelmintic, nematicidal and anti-protozoal activities.
This study was conducted to investigate the immunological patterns in rats infected with T. gondii who were treated orally with supplemented 15% Capparis spinosa honey (Saudi Arabia) for a period of 28 days.
Methods: Immunoglobulin M, immunoglobulin G, and cytokines were detected by using enzyme-linked immunosorbent assays (ELISAs). In addition, the mortality and the morbidity rates were assessed.
Results: Oral administration of Capparis spinosa honey as a natural food additive was experimentally shown to increase the antibody titer; furthermore, compared with the rats in the control group, the levels of the sera cytokines (IFN-γ, IL-1 and IL-6) were consistently higher at day 7 post-infection in the infected rats treated with oral supplements of Capparis spinosa honey.
Conclusion: Orally administered supplements of Capparis spinosa honey increased both the antibody titer and the cytokines (IFN-γ, IL-1 and IL-6) levels in rats infected with T. gondii.
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참고문헌 (64)
참고문헌 신청
Joynson DH / 2001 / Toxoplasmosis: a comprehensive clinical guide / Cambridge University Press :412
McConkey GA / 2003 / Toxoplasma gondii infection and behaviorr-location, location, location? / J Exp Biol 216(1):113~119
Dawkins R. / 1999 / The extended phenotype: the long reach of the gene / Oxford University Press :336
Luder CG / 1999 / Toxoplasma gondii in primary rat CNS cells: differential contribution of neurons, astrocytes, and microglial cells for the intracerebral development and stage dif-ferentiation / Exp Parasitol 93(1):23~32
Vidotto O / 1990 / Estudos epidemiológicos da toxoplasmose em suínos da região de Londrina, PR / Semina Cien Agrárias 11(1):53~59
McConkey GA / 2003 / Toxoplasma gondii infection and behaviorr-location, location, location? / J Exp Biol 216(1):113~119
Dawkins R. / 1999 / The extended phenotype: the long reach of the gene / Oxford University Press :336
Luder CG / 1999 / Toxoplasma gondii in primary rat CNS cells: differential contribution of neurons, astrocytes, and microglial cells for the intracerebral development and stage dif-ferentiation / Exp Parasitol 93(1):23~32
Vidotto O / 1990 / Estudos epidemiológicos da toxoplasmose em suínos da região de Londrina, PR / Semina Cien Agrárias 11(1):53~59
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