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논문 기본 정보

자료유형
학술저널
저자정보
Dina Eskandere (Department of Gastroenterology and Hepatology Mansoura University Mansoura Egypt) Hazem Hakim (Department of Gastroenterology and Hepatology Mansoura University Mansoura Egypt) Magdy Attwa (Department of Gastroenterology and Hepatology Mansoura University Mansoura Egypt) Wagdi Elkashef (Department of Pathology Mansoura University Mansoura Egypt) Ahmed Youssef Altonbary (Department of Gastroenterology and Hepatology Mansoura University Mansoura Egypt)
저널정보
대한소화기내시경학회 Clinical Endoscopy Clinical Endoscopy 제54권 제5호
발행연도
2021.9
수록면
745 - 753 (9page)
DOI
10.5946/ce.2020.240

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Background/Aims: Malignant portal vein thrombus (PVT) is found in up to 44% of patients with hepatocellular carcinoma (HCC). The nature of the thrombus influences treatment selection. The aim of this study was to assess the safety and efficacy of endoscopicultrasound-guided fine-needle aspiration (EUS-FNA) in determining the nature of PVT in liver cirrhosis and/or HCC. Methods: A prospective study was conducted in 34 patients with liver cirrhosis and/or HCC with PVT. Under EUS guidance, PVTwas punctured using a 22 G FNA needle (Cook Medical, Bloomington, IN, USA) followed by monitoring of the puncture tract usingcolor Doppler. Patients were followed for adverse events 2 hours after recovery. Results: Throughout the 30-month study period, 34 patients, including 24 males with a mean age of 59±8 years, were enrolled. There were 8 patients with known HCC and 26 with no liver masses detected by computed tomography (CT). EUS-FNA from PVTwas positive for malignancy in 3 patients (8.8%), of which only 1 patient was diagnosed with HCC by CT and 2 patients were newlydiagnosed with HCC after EUS-FNA. No major complications were reported. Conclusions: EUS-FNA is a safe and effective technique for determining the nature of PVT that does not fulfill the malignant criteriavia imaging studies in patients with liver cirrhosis and/or HCC.

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