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논문 기본 정보

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학술저널
저자정보
Tadayuki Takagi (Department of Gastroenterology School of Medicine Fukushima Medical University Fukushima Japan) Mitsuru Sugimoto (Department of Gastroenterology School of Medicine Fukushima Medical University Fukushima Japan) Hidemichi Imamura (Department of Gastroenterology Ohtanishinouchi Hospital Koriyama Japan) Yosuke Takahata (Department of Gastroenterology Aizu Medical Center Fukushima Medical University Aizuwakamatsu Japan) Yuki Nakajima (Department of Gastroenterology Aizu Medical Center Fukushima Medical University Aizuwakamatsu Japan) Rei Suzuki (Department of Gastroenterology School of Medicine Fukushima Medical University Fukushima Japan) Naoki Konno (Department of Gastroenterology School of Medicine Fukushima Medical University Fukushima Japan) Hiroyuki Asama (Department of Gastroenterology School of Medicine Fukushima Medical University Fukushima Japan) Yuki Sato (Department of Gastroenterology School of Medicine Fukushima Medical University Fukushima Japan) Hiroki Irie (Department of Gastroenterology School of Medicine Fukushima Medical University Fukushima Japan) Jun Nakamura (Department of Endoscopy Fukushima Medical University Hospital Fukushima Japan) Mika Takasumi (Department of Gastroenterology School of Medicine Fukushima Medical University Fukushima Japan) Minami Hashimoto (Department of Endoscopy Fukushima Medical University Hospital Fukushima Japan) Tsunetaka Kato (Department of Endoscopy Fukushima Medical University Hospital Fukushima Japan) Ryoichiro Kobashi (Department of Endoscopy Fukushima Medical University Hospital Fukushima Japan) Yuko Hashimoto (Department of Diagnostic Pathology School of Medicine Fukushima Medical University Fukushima Japan) Goro Shibukawa (Department of Gastroenterology Aizu Medical Center Fukushima Medical University Aizuwakamatsu Japan) Shigeru Marubashi (Department of Hepato-Biliary-Pancreatic and Transplant Surgery School of Medicine Fukushima Medical University Fukushima Japan) Takuto Hikichi (Department of Endoscopy Fukushima Medical University Hospital Fukushima Japan) Hiromasa Ohira (Department of Gastroenterology School of Medicine Fukushima Medical University Fukushima Japan)
저널정보
대한소화기내시경학회 Clinical Endoscopy Clinical Endoscopy 제56권 제1호
발행연도
2023.1
수록면
107 - 113 (7page)
DOI
10.5946/ce.2022.019

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high tumors. Therefore, sufficient sampling of histological specimens is necessary in cases of unresectable pancreatic cancer (UR-PC). This multicenter study investigated the efficacy of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) using a Franseen needlefor MSI evaluation in patients with UR-PC. Methods: A total of 89 patients with UR-PC who underwent endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) orEUS-FNB using 22-G needles at three hospitals in Japan (2018–2021) were enrolled. Fifty-six of these patients (FNB 23 and FNA 33)were followed up or evaluated for MSI. Patient characteristics, UR-PC data, and procedural outcomes were compared between patientswho underwent EUS-FNB and those who underwent EUS-FNA. Results: No significant difference in terms of sufficient tissue acquisition for histology was observed between patients who underwentEUS-FNB and those who underwent EUS-FNA. MSI evaluation was possible significantly more with tissue samples obtained usingEUS-FNB than with tissue samples obtained using EUS-FNA (82.6% [19/23] vs. 45.5% [15/33], respectively; p<0.01). In the multivariateanalysis, EUS-FNB was the only significant factor influencing the possibility of MSI evaluation. Conclusions: EUS-FNB using a Franseen needle is desirable for ensuring sufficient tissue acquisition for MSI evaluation.
#Endoscopic ultrasound-guided fine-needle aspiration #Endoscopic ultrasound-guided fine-needle biopsy #Franseen needle #Microsatellite instability #Pancreatic neopla는

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