지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.8
- 수록면
- 769 - 777 (9page)
- DOI
- https://doi.org/10.3803/EnM.2021.1109
이용수
초록· 키워드
오류제보하기
Background: Data on the association between coronavirus disease 2019 (COVID-19) and thyroid have been reported, includingovert thyrotoxicosis and suppression of thyroid function. We aimed to evaluate the thyroid hormone profile and its association withthe prognosis of COVID-19 in Korean patients.
Methods: The clinical data of 119 patients with COVID-19, admitted in the Myongji Hospital, Goyang, South Korea, were retrospectively evaluated. The thyroid hormone profiles were analyzed and compared based on disease severity (non-severe disease vs.
severe to critical disease). Clinical outcomes were analyzed according to the tertiles of thyroid hormones.
Results: Of the 119 patients, 76 (63.9%) were euthyroid, and none presented with overt thyroid dysfunction. Non-thyroidal illnesssyndrome was the most common manifestation (18.5%), followed by subclinical thyrotoxicosis (14.3%) among patients with thyroiddysfunction. Thyroid stimulating hormone (TSH) and triiodothyronine (T3) levels were significantly lower in patients with severe tocritical disease than in those with non-severe disease (P<0.05). Patients in the lowest T3 tertile (<0.77 ng/mL) had higher rates ofmechanical ventilation, intensive care unit admission, and death than those in the middle and highest (>1.00 ng/mL) T3 tertiles(P<0.05). COVID-19 patients in the lowest T3 tertile were independently associated with mortality (hazard ratio, 5.27; 95% confidence interval, 1.09 to 25.32; P=0.038) compared with those in the highest T3 tertile.
Conclusion: Thyroid dysfunction is common in COVID-19 patients. Changes in serum TSH and T3 levels may be important markers of disease severity in COVID-19. Decreased T3 levels may have a prognostic significance in COVID-19 related outcome.
목차
등록된 정보가 없습니다.
참고문헌 (2)
참고문헌 신청
David Tak Wai Lui / 2021 / Role of non‐thyroidal illness syndrome in predicting adverse outcomes in COVID‐19 patients predominantly of mild‐to‐moderate severity / Clinical Endocrinology 95(3):469~477
장민철 / 2020 / Fasting Plasma Glucose Level Independently Predicts the Mortality of Patients with Coronavirus Disease 2019 Infection: A Multicenter, Retrospective Cohort Study / Endocrinology and Metabolism 35(3):595~601
장민철 / 2020 / Fasting Plasma Glucose Level Independently Predicts the Mortality of Patients with Coronavirus Disease 2019 Infection: A Multicenter, Retrospective Cohort Study / Endocrinology and Metabolism 35(3):595~601
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Changes in thyroid hormones in patients undergoing liver transplantation
Anesthesia and Pain Medicine
2015 .01
-
Stress Affects Thyroid Stimulating Hormone and Thyroid Hormone in the Patients Who Underwent Thyroidectomy
The Journal of Endocrine Surgery
2024 .03
-
COVID-19 유행 시기의 갑상선질환 관리
International Journal of Thyroidology
2020 .01
-
Insights from a Prospective Follow-up of Thyroid Function and Autoimmunity among COVID-19 Survivors
Endocrinology and Metabolism
2021 .01
-
이해하기 어려운 갑상선기능검사의 해석
대한의사협회지
2018 .01
-
A Multicenter, Randomized, Controlled Trial for Assessing the Usefulness of Suppressing Thyroid Stimulating Hormone Target Levels after Thyroid Lobectomy in Low to Intermediate Risk Thyroid Cancer Patients (MASTER): A Study Protocol
Endocrinology and Metabolism
2021 .01
-
Reference Intervals for Thyroid-Associated Hormones and the Prevalence of Thyroid Diseases in the Chinese Population
Annals of Laboratory Medicine
2021 .01
-
분화갑상선암 수술 후 갑상선자극호르몬 억제요법과 골다공증
The Journal of Endocrine Surgery
2016 .01
-
Association between D-dimer and long-term mortality in patients with acute severe hypertension visiting the emergency department
Clinical Hypertension
2023 .01
-
조현병 입원 환자에서의 갑상샘 기능이상과 증상 심각도, 치료 반응과의 관계
생물정신의학
2019 .01
-
Thyroid Hormone Resistance in a Preterm Infant with a Novel THRB Mutation
Neonatal medicine
2019 .01
-
Diagnosis and Management of Thyroid Disease during Pregnancy and Postpartum: 2023 Revised Korean Thyroid Association Guidelines
Endocrinology and Metabolism
2023 .06
-
Thyroid dysfunction and subfertility
Clinical and experimental reproductive medicine : CERM
2015 .01
-
Evaluation and Management of Bone Health in Patients with Thyroid Diseases: A Position Statement of the Korean Thyroid Association
Endocrinology and Metabolism
2023 .04
-
미숙아와 아픈 신생아의 갑상선 장애
Neonatal medicine
2015 .01
-
Postoperative Thyroid-Stimulating Hormone Levels Did Not Affect Recurrence after Thyroid Lobectomy in Patients with Papillary Thyroid Cancer
Endocrinology and Metabolism
2019 .01
-
Subclinical Hypothyroidism Affects the Long-Term Outcomes of Patients Who Undergo Coronary Artery Bypass Grafting Surgery but Not Heart Valve Surgery
Endocrinology and Metabolism
2020 .01
-
Prognostic Factors for Severe Coronavirus Disease 2019 in Daegu, Korea
Journal of Korean Medical Science
2020 .01
-
Laboratory Testing in Thyroid Conditions – Pitfalls and Clinical Utility
Annals of Laboratory Medicine
2019 .01
-
Thyroid : Cons
대한임상종양학회 학술대회지
2015 .02
이 논문의 저자 정보
최근 본 자료
댓글(0)
0