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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.8
- 수록면
- 728 - 734 (7page)
- DOI
- 10.9799/ksfan.2017.30.4.728
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After being subjected to different cooking methods, small black beans (Rhynchosia nulubilis) were investigated in order to assess the effects of the retained bioactive compounds. Using uncooked, pan broiled, boiled, steamed, and pressure cooked beans, the inhibitory effects of MCF-7 cell migration were evaluated at protein concentrations of 40, 160, and 640 μm/mL, using the Boyden's chamber assay. All protein concentrations (40, 160, and 640 μm/mL) of pan broiled beans showed significant reduction (59.83, 32.48, and 21.37%, respectively) in the rate of cell migration to the lower chambers (p-value less than 0.001). Estimated cell migration rates correlated to the exponential decay between experimentally measured cell migration rates and converted samples. The range of estimated cell migration rate for each 100 mg/mL of cooked sample was as follows: pan broiled (21.16%), boiled (22.48%), steamed (22.48%), pressure cooked (29.52%), and uncooked (35.03%) beans. Our study indicated that selective modifications of cooking methods for small black beans, such as pan broiling, ameliorated the inhibitory effects of MCF-7 cell migration. This suggests that optimized cooking methods increase the nutritional contents of the cooked food.
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참고문헌 (23)
참고문헌 신청
방명희 / 2006 / Curcumin이 인체 유방암세포 MDA-MB-231 Cell의 전이 과정과 Matrix Metalloproteinase-9 활성에 미치는 영향 / Journal of Nutrition and Health 39(8):756~761
Bradford MM / 1976 / Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding / Anal Biochem 72:248~254
Choung MG / 2001 / Isolation and determination of anthocyanins in seed coats of black soybean(Glycine max(L. )Merr. ) / J Agric Food Chem 49:5848~5851
Farina HG / 2006 / Antitumor and antiangiogenic activity of soy isoflavone genistein in mouse models of melanoma and breast cancer / Oncology Reports 16:885~891
Ford LA / 2010 / A role for L-α-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells / British J Pharm 160:762~771
Bradford MM / 1976 / Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding / Anal Biochem 72:248~254
Choung MG / 2001 / Isolation and determination of anthocyanins in seed coats of black soybean(Glycine max(L. )Merr. ) / J Agric Food Chem 49:5848~5851
Farina HG / 2006 / Antitumor and antiangiogenic activity of soy isoflavone genistein in mouse models of melanoma and breast cancer / Oncology Reports 16:885~891
Ford LA / 2010 / A role for L-α-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells / British J Pharm 160:762~771
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