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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.4
- 수록면
- 251 - 256 (6page)
- DOI
- 10.9799/ksfan.2017.30.2.251
이용수
초록· 키워드
오류제보하기
This study aimed to assess fatty acid composition and anti-inflammatory effects, such as nitric oxide(NO) production, expression of TNF-α and interleukin-6(IL-6), of Tenebrio molitor larva using RAW 264.7 cells. The content of total fatty acid in Tenebrio molitor larva was 76.14%, which was composed of oleic acid(42.12%), linoleic acid(32.67%) etc. There was no cytotoxicity at a dose level of 0.1, 1.0, 10, and 100 μg/mL of freeze dried Tenebrio molitor larva ethanol extract(FDTEtOH) on RAW 264.7 cells. FDTEtOH significantly decreased NO production in LPS(lipopolysaccharide)- stimulated RAW 264.7 cells in a dose-dependent manner. Also, FDTEtOH dose-dependently suppressed the expression of TNF-α and IL-6. Thus, these results showed that Tenebrio molitor larva has the potential to be used as an anti-inflammatory food to improve immunity.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Bukkens SG / 1997 / The nutritional value of edible insects / Ecol Food Nutr 36:287~319
Carluccio MA / 1999 / Oleic acid inhibits endothelial activation : A direct vascular antiatherogenic mechanism of a nutritional component in the mediterranean diet / Arterioscler Thromb Vasc Biol 9:220~228
Chunfa H / 2015 / Lipid metabolism, apoptosis and cancer therapy / Int J Molecular Sci 16:924~949
Chung MY / 2013 / Pretreatment conditions on the powder of Tenbrio molitor for using as a novel food ingredient / J Seric Entomol Sci 51:9~14
Dinarello DA / 1991 / Interleukin-1, anorexia, and dietary fatty acid / Ann NY Acad Sci 1:332
Carluccio MA / 1999 / Oleic acid inhibits endothelial activation : A direct vascular antiatherogenic mechanism of a nutritional component in the mediterranean diet / Arterioscler Thromb Vasc Biol 9:220~228
Chunfa H / 2015 / Lipid metabolism, apoptosis and cancer therapy / Int J Molecular Sci 16:924~949
Chung MY / 2013 / Pretreatment conditions on the powder of Tenbrio molitor for using as a novel food ingredient / J Seric Entomol Sci 51:9~14
Dinarello DA / 1991 / Interleukin-1, anorexia, and dietary fatty acid / Ann NY Acad Sci 1:332
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