지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 400 - 407 (8page)
- DOI
- https://doi.org/10.3904/kjm.2021.96.5.400
이용수
초록· 키워드
오류제보하기
Adult growth hormone (GH) deficiency is associated with insulin resistance, elevated cardiovascular risk profile, increased fat mass, reduced muscle mass, skeletal fragility, and impaired quality of life. GH replacement therapy improves body composition, exercise capacity, skeletal health, cardiovascular outcomes, and quality of life, while reducing mortality. Prior to initiation of GH replacement therapy, it is essential to diagnose GH deficiency via a GH stimulation test in adults suspicious of such deficiency.
Therapy should be started using (individualized) low dose of GH, followed by titration to the normal range of insulin-like growth factor-1. Clinical improvements should be monitored and side effects should be minimized.
목차
등록된 정보가 없습니다.
참고문헌 (44)
참고문헌 신청
Weaver JU / 1995 / The effect of low dose recombinant human growth hormone replacement on regional fat distribution, insulin sensitivity, and cardiovascular risk factors in hypopituitary adults / J Clin Endocrinol Metab 80:153~159
Beshyah SA / 1999 / Cardiovascular disease and risk factors in adults with hypopituitarism / Clin Endocrinol(Oxf) 50:1~15
Khang AR / 2016 / Sex differences in the prevalence of metabolic syndrome and its components in hypopituitary patients : comparison with an age-and sex-matched nationwide control group / Pituitary 19:573~581
김정희 / 2020 / Diagnosis and Treatment of Growth Hormone Deficiency: A Position Statement from Korean Endocrine Society and Korean Society of Pediatric Endocrinology / Endocrinology and Metabolism 35(2):272~287
Yuen KCJ / 2019 / American Association of Clinical Endocrinologists and American College of Endocrinology guidelines for management of growth hormone deficiency in adults and patients transitioning from pediatric to adult care / Endocr Pract 25:1191~1232
Beshyah SA / 1999 / Cardiovascular disease and risk factors in adults with hypopituitarism / Clin Endocrinol(Oxf) 50:1~15
Khang AR / 2016 / Sex differences in the prevalence of metabolic syndrome and its components in hypopituitary patients : comparison with an age-and sex-matched nationwide control group / Pituitary 19:573~581
김정희 / 2020 / Diagnosis and Treatment of Growth Hormone Deficiency: A Position Statement from Korean Endocrine Society and Korean Society of Pediatric Endocrinology / Endocrinology and Metabolism 35(2):272~287
Yuen KCJ / 2019 / American Association of Clinical Endocrinologists and American College of Endocrinology guidelines for management of growth hormone deficiency in adults and patients transitioning from pediatric to adult care / Endocr Pract 25:1191~1232
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