지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.12
- 수록면
- 409 - 412 (4page)
- DOI
- https://doi.org/10.3904/kjm.2020.95.6.409
이용수
초록· 키워드
오류제보하기
Mixed connective tissue disease (MCTD) is a rheumatologic disorder that has combined features of systemic lupus erythematosus, systemic sclerosis, and rheumatoid arthritis with the anti-U1 ribonucleoprotein (RNP) antibody. Although renal involvement is not included in any of the diagnostic criteria, it has been observed in 20% of MCTD patients. The most common renal disease is immune complex nephropathy, histologically classified as membranous glomerulonephritis, but minimal change disease (MCD) is very rare and has only been reported once previously. A previously healthy 33-year-old woman presented with generalized edema, puffy hands, arthralgia, and Raynaud’s phenomenon. We diagnosed MCD with proteinuria (> 9 g/day) and hypoalbuminemia (< 1.0 g/dL) by renal biopsy, and MCTD with a simultaneously high titer of the anti-U1 RNP antibody. The patient was treated with 200 mg/day cyclosporine and 30 mg/day prednisolone. The proteinuria and hypoalbuminemia normalized 2 months later. We report a patient with severe MCD associated with MCTD.
목차
등록된 정보가 없습니다.
참고문헌 (9)
참고문헌 신청
Gunnarsson R / 2016 / Mixed connective tissue disease / Best Pract Res Clin Rheumatol 30:95~111
Kitridou RC / 1986 / Renal involvement in mixed connective tissue disease : a longitudinal clinicopathologic study / Semin Arthritis Rheum 16:135~145
Sharp GC / 1972 / Mixed connective tissue disease--an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen(ENA) / Am J Med 52:148~159
Kobayashi S / 1985 / Renal involvement in mixed connective tissue disease. Report of 5 cases / Am J Nephrol 5:282~289
Yoshida A / 1994 / Nephropathy in patients with mixed connective tissue disease / Ryumachi 34:976~980
Kitridou RC / 1986 / Renal involvement in mixed connective tissue disease : a longitudinal clinicopathologic study / Semin Arthritis Rheum 16:135~145
Sharp GC / 1972 / Mixed connective tissue disease--an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen(ENA) / Am J Med 52:148~159
Kobayashi S / 1985 / Renal involvement in mixed connective tissue disease. Report of 5 cases / Am J Nephrol 5:282~289
Yoshida A / 1994 / Nephropathy in patients with mixed connective tissue disease / Ryumachi 34:976~980
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