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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.9
- 수록면
- 90 - 96 (7page)
- DOI
- https://doi.org/10.11149/jkaoh.2018.42.3.90
이용수
초록· 키워드
오류제보하기
Objectives: The purpose of this study was to investigate the combined effects of Galla chinensis extract(GCE) and calcium (CA) on enamel remineralization. The antibacterial effect of G. chinensis onStreptococcus mutans biofilm was also evaluated by examining the bacterial growth, acidogenesis, andmorphology of the biofilm in vitro.
Methods: S. mutans biofilm was formed on bovine enamel specimens over a 72-h period and treatedfor 10 min with 1.0 mol CA, 4,000 ppm aqueous solution of GCE, or a combination of the two (GCE+CA).
The enamel specimens were analyzed for enamel surface microhardness after remineralization. Wetested the anti-cariogenic effects of GCE based on the inhibition of acid production, antibacterial activity,and morphological changes in S. mutans. The differences between the groups and antibacterial effectswere analyzed using one-way analysis of variance.
Results: GCE+CA group showed the highest efficacy in enhancing remineralization. The GCE groupshowed the highest antibacterial activity against S. mutans biofilm. Although the GCE+CA groupshowed significant antibacterial activity, it was less than that of the GCE group (P<0.05). Both GCE andGCE+CA groups maintained a pH of approximately 7.0 for 1 h whereas the pH of the control groupdecreased rapidly from pH 7.3 to pH 6.1. SEM imaging revealed that S. mutans treated with GCE andGCE+CA showed irregular cell wall structure and showed fewer cells in the chain than the typical longchains observed in the control group.
Conclusions: This study found that natural G. chinensis significantly enhances enamel remineralization,and exerts synergistic effects with calcium. It also exerts strong bactericidal activity and inhibits acid productionand changes in the microstructure of S. mutans biofilm.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Cheng L / 2009 / Effect of Galla Chinensis on enhancing remineralization of enamel crystals / Biomed Mater 4:1~6
Zero DT / 1999 / Dental caries process / Dent Clin North Am 43:635~664
Phan TN / 2006 / Triclosan inhibition of membrane enzymes and glycolysis of Streptococcus mutans in suspensions and biofilms / Can J Microbiol 52:977~983
Jeon J / 2011 / Natural products in caries research: current (limited) knowledge, challenges and future perspective / Caries Res 45:243~263
Palombo EA / 2011 / Traditional medicinal plant extracts and natural products with activity against oral bacteria: potential application in the prevention and treatment of oral disease / Evid Based Complement Alternat Med :1~15
Zero DT / 1999 / Dental caries process / Dent Clin North Am 43:635~664
Phan TN / 2006 / Triclosan inhibition of membrane enzymes and glycolysis of Streptococcus mutans in suspensions and biofilms / Can J Microbiol 52:977~983
Jeon J / 2011 / Natural products in caries research: current (limited) knowledge, challenges and future perspective / Caries Res 45:243~263
Palombo EA / 2011 / Traditional medicinal plant extracts and natural products with activity against oral bacteria: potential application in the prevention and treatment of oral disease / Evid Based Complement Alternat Med :1~15
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