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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.3
- 수록면
- 3 - 8 (6page)
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Objectives: This study aims to identify and partially purify antibacterial compounds against Streptococcus mutans from Galla Rhois extract. Methods: Galla Rhois was extracted with n-hexane or ethanol and concentrated in a rotary evaporator. The antibacterial effect of the Galla Rhois extract against S. mutans was determined by the paper discdiffusion method with n-hexane, ethanol, methanol, ethyl acetate, dimethyl sulfoxide (DMSO), acetone, and distilled water as the solvents. The active compounds were purified by partition chromatography, thin-layer chromatography (TLC), and high-performance liquid chromatography (HPLC). Results: The antibacterial effect of the n-hexane extract was more effective against S. mutans than the ethanol extract ( P <0.05). The antibacterial component of Galla Rhois was partially purified using partition chromatography and HPLC, and the antibacterial activity was confirmed. Conclusions: The partially purified component of Galla Rhois showed strong antibacterial effect against S. mutans . These results confirm that the antibacterial compounds of Galla Rhois can be used for the prevention of dental caries.
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참고문헌 (21)
참고문헌 신청
Marsh P / 1999 / Oral microbiology / Wright :82~103
Bakri IM / 2005 / Inhibitory effect of garlic extract on oral bacteria / Arch Oral Biol 50:645~651
Islam B / 2008 / Novel anti-adherence activity of mulberry leaves: inhibition of Streptococcus mutans biofilm by 1-deoxynojirimycin isolated from Morus alba / J Antimicrob Chemother 62:751~757
Naderi NJ / 2011 / Antibacterial activity of iranian green and black tea on Streptococcus mutans: An in vitro study / J Dent 8(2):55~59
Xu X / 2011 / The tea catechin epigallocatechin gallate suppresses cariogenic virulence factors of Streptococcus mutans / Antimicrob Agents Chemother 55(3):1229~1236
Bakri IM / 2005 / Inhibitory effect of garlic extract on oral bacteria / Arch Oral Biol 50:645~651
Islam B / 2008 / Novel anti-adherence activity of mulberry leaves: inhibition of Streptococcus mutans biofilm by 1-deoxynojirimycin isolated from Morus alba / J Antimicrob Chemother 62:751~757
Naderi NJ / 2011 / Antibacterial activity of iranian green and black tea on Streptococcus mutans: An in vitro study / J Dent 8(2):55~59
Xu X / 2011 / The tea catechin epigallocatechin gallate suppresses cariogenic virulence factors of Streptococcus mutans / Antimicrob Agents Chemother 55(3):1229~1236
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