갑상선 여포암과 휘틀세포암의 임상양상과 예후인자에 대한 비교 연구

김정준; 김브라이언; 최익준; 이병철; 안정민; 공준석; 이명철

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자료유형: 학술저널

저자정보: 김정준 (원자력병원) 김브라이언 (한국원자력의학원 원자력병원 이비인후-두경부외과) 최익준 (원자력병원) 이병철 (원자력병원) 안정민 (한국원자력의학원 원자력병원 이비인후-두경부외과) 공준석 (한국원자력의학원 원자력병원 병리과) 이명철 (한국원자력의학원 원자력병원 이비인후-두경부외과)

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후-두경부외과학회지 제64권 제12호

발행연도: 2021.12

수록면: 906 - 913 (8page)

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Background and Objectives Follicular thyroid carcinoma (FTC) is the second commonthyroid cancer which comprises about 10% of differentiated thyroid carcinoma. Hurthle cellcarcinoma (HCC) is a relatively rare disease that has been classified as a subtype of FTC. However, there have been insufficient reports about these two similar thyroid cancers in SouthKorea due to low incidences. This study aims to present clinical features and evaluate prognosticfactors of FTC and HCC. Subjects and Method We reviewed data of 189 FTC and 12 HCC patients who underwentsurgery in our center from January 2000 to December 2020. Variables such as clinical characteristics,surgical method, pathologic result, post-operative treatment, survival rate and prognosticfactors were included in our study. Results As for age, 67.2% of patients in FTC group and 33.3% of patients in HCC groupwere older than 55 years-old (p=0.017). The average tumor sizes of FTC and HCC were 2.98and 3.1 cm, respectively. The 10-year overall survival rates of FTC and HCC were 96.5% and100%, respectively. The 10-year disease free survival rates of FTC and HCC were 89.1% and91.7%, respectively. Subclassification (widely invasive: p=0.036) and initial distant metastasis(p<0.001) were significant prognostic factors in FTC. Conclusion This study will be helpful for diagnosis and treatment of FTC and HCC, whichare relatively rare.

#Carcinoma #Follicular carcinoma #Hurthle cell #Prognosis #Thyroid.

참고문헌 (26)

참고문헌 신청

Varadarajan VV / 2017 / Follicular thyroid carcinoma metastasis to the facial skeleton : A systematic review / BMC Cancer 17(1):225

모정아 / 2010 / 갑상선 여포암의 임상양상과 고찰 / 대한이비인후-두경부외과학회지 53(1):30~36

Kakudo K / 2018 / The new 4th edition World Health Organization classification for thyroid tumors, Asian perspectives / Pathol Int 68(12):641~664

김정준 / 2020 / 갑상선의 휘틀세포암 12예 / 대한이비인후-두경부외과학회지 63(12):615~619

Lopez-Penabad L / 2003 / Prognostic factors in patients with Hürthle cell neoplasms of the thyroid / Cancer 97(5):1186~1194

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