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논문 기본 정보

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학술저널
저자정보
Kim Minjae (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) 황신 (울산대학교) Ahn Chul-Soo (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) Moon Deok-Bog (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) Ha Tae-Yong (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) Song Gi-Won (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) Jung Dong-Hwan (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) Park Gil-Chun (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) Kim Ki-Hun (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) Jung-Man Namgoong (Department of Surgery Asan Medical Center University of Ulsan College of Medicine Seoul Korea) Kang Woo-Hyoung (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) Yoon Young-In (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) Cho Hwui-Dong (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) Na Byeong-Gon (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) Kim Sang Hoon (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent) Lee Sung-Gyu (Division of Hepatobiliary Surgery and Liver Transplantation Department of Surgery Asan Medical Cent)
저널정보
대한이식학회 Clinical Transplantation and Research Korean Journal of Transplantation Vol.36 No.1
발행연도
2022.3
수록면
45 - 53 (9page)
DOI
10.4285/kjt.21.0031

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Background: The outcomes of liver transplantation (LT) have improved, but actual 20- year survival data have rarely been presented. Methods: Longitudinal follow-up data of 20-year LT survivors were retrospectively analyzed. The LT database of our institution was searched to identify patients who underwent primary LT from January 2000 to December 2001. The study cohort of 251 patients was divided into three groups: 207 adults who underwent living donor LT (LDLT), 22 adults who underwent deceased donor LT (DDLT), and 22 pediatric patients who underwent LT. Results: Hepatitis B virus?associated liver cirrhosis and biliary atresia were the most common indications for adult and pediatric LT, respectively. Seven patients required retransplantation, including six who underwent DDLT and one who underwent LDLT. Twenty- two patients died within 3 months after LT and 69 died at later intervals. The overall survival rates at 1, 3, 5, 10, and 20 years were 86.4%, 79.6%, 77.7%, 72.8%, and 62.6%, respectively, in the adult LDLT group; 86.4%, 72.7%, 72.7%, 72.7%, and 68.2%, respectively, in the adult DDLT group; and 86.4%, 86.4%, 81.8%, 81.8%, and 77.3%, respectively, in the pediatric LT group (P=0.545). Common immunosuppressive regimens at 20 years included tacrolimus monotherapy, tacrolimus?mycophenolate dual therapy, cyclosporine monotherapy, and mycophenolate monotherapy. Conclusions: The present study is the first report of actual 20-year survival data from a Korean high-volume LT center. The graft and patient survival outcomes reflected the early experiences of LT in our institution, with long-term outcomes being similar regardless of graft type and patient age.
#Living donor #Deceased donor #Donor shortage #Long-term follow-up #Perioperative mortality

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