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Fertility preservation in women: where we are now and the path we need to take
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가임력 보존의 현재와 앞으로 나아갈 길

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Type
Academic journal
Author
Jisun Lee (경북대학교 의과대학 경북대학교병원 산부인과) LEE TAEK HOO (경북대학교 의과대학 경북대학교병원 산부인과)
Journal
Korean Medical Association 대한의사협회지 대한의사협회지 제65권 제6호 KCI Accredited Journals
Published
2022.6
Pages
316 - 320 (5page)
DOI
https://doi.org/10.5124/jkma.2022.65.6.316

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Fertility preservation in women: where we are now and the path we need to take
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Background: In its short history, reproductive medicine has achieved many fertility-related milestones, including: the arrival of in vitro fertilization in the late 1970s, the development of intracytoplasmic sperm injection in the early 1990s, the first ovarian transplant a decade ago, and the first livebirth after uterine transplantation in 2014. This paper provides a brief overview of the indications and methods, as well as future perspectives, available for fertility preservation. Current Concepts: More women are undergoing fertility preservation for medical or social reasons. Fertility preservation aids cancer patients in retaining the ability to procreate. Despite the high survival rate of malignancies in young patients, chemotherapy and whole abdominal irradiation have cytotoxic effects on reproductive organs. Cancer treatments can significantly reduce a patient’s reproductive capacity and thus result in irreversible infertility. Early ovarian failure is also a common by-product of additional cancer treatment, bone marrow transplantation, or autologous transplantation. The current options for fertility preservation in cancer patients include cryopreservation (of embryos, oocytes, and ovarian tissue) and gonadotropic-releasing hormone agonist treatment (before and during chemotherapy). Fertility preservation is a means for female cancer patients to preserve their fertility and delay childbearing. Fertility preservation can also aid women who wish to delay childbearing for personal reasons. Since the indications for fertility preservation are different for each patient, individualized treatment strategies should be employed depending on the patient’s situation. Discussion and Conclusion: Health professionals must inform women who are undergoing cancer treatments or purposefully delaying childbearing about the risks of decreased fertility. Appropriate fertility preservation options must be provided for these female patients.
#가임력 보존 #화학요법 #방사선치료 #냉동 보존 #난소예비능 #Fertility preservation #Chemotherapy #Radiotherapy #Cryopreservation #Ovarian reserve

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