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자료유형
학술저널
저자정보
저널정보
대한산부인과학회 Obstetrics & Gynecology Science Obstetrics & Gynecology Science 제61권 제4호
발행연도
2018.1
수록면
443 - 452 (10page)

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Adolescent and young adult (AYA) patients are generally defined as being from 15 to 39 years old. For preservation offertility in AYA cancer patients, the best-known guideline in this field was released by the American Society of ClinicalOncology (ASCO) in 2006. However, the ASCO guideline is not necessarily applicable to Japanese cancer patients. TheJapan Society for Fertility Preservation (JSFP) was formed in 2012, and a system and guideline for fertility preservationin Japanese AYA cancer patients plus children was released in July 2017. According to this guideline, patientsshould receive psychological and social support from health care providers such as doctors, nurses, psychologists,pharmacists, and social workers. In 2013, the American Society for Reproductive Medicine stated that freezingoocytes is a method that has passed beyond the research stage. However, freezing ovarian tissue is still a researchprocedure. While slow freezing of ovarian tissue is generally performed, rapid freezing (vitrification) is more popularin Japan. We have developed a new closed technique for ovarian tissue cryopreservation. It has been suggested thatoptical coherence tomography might be applied clinically to measure the true ovarian reserve and localize folliclesin patients undergoing ovarian tissue transplantation. Combining gonadotropin-releasing hormone agonist therapywith anticancer agents might be useful for ovarian protection and it is expected that discussion of such combinedtreatment will continue in the future. This article outlines practical methods of fertility preservation using assistedreproductive techniques for AYA cancer patients in Japan.

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