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논문 기본 정보

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학술저널
저자정보
김현정 (서울시립대학교) 윤자경 (세종병원) 김철호 (Mayo Clinic) 김성호 (세종병원 소아청소년과) Barry A Franklin (William Beaumont Hospital) 제세영 (서울시립대학교)
저널정보
대한스포츠의학회 대한스포츠의학회지 대한스포츠의학회지 제40권 제2호
발행연도
2022.6
수록면
86 - 93 (8page)
DOI
10.5763/kjsm.2022.40.2.86

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Purpose: Although chronotropic incompetence (CI) is common in patients with complex congenital heart disease (CHD) and is associated with adverse cardiovascular outcomes, few data are available regarding modifiable predictors of CI in this escalating patient population. We tested the hypothesis that higher levels of physical activity (PA) are associated with a lower prevalence of CI in patients with complex CHD and evaluated the receiver operating characteristic curve to identify the PA level that best predicted CI. Methods: We evaluated 111 adolescents with complex CHD. CI was defined as the failure to achieve 80% of the chronotropic response index during peak cardiopulmonary exercise test. Self-reported habitual activity was obtained using a global PA questionnaire. Results: CI was identified in 45 of the 111 cases (40.5%). After adjusting for potential confounding variables, the high PA group demonstrated a lower odds ratio for having CI (odds ratios, 0.25; 95% confidence interval, 0.06?0.99) compared with the low PA group. The most accurate cut-point for PA to predict the prevalence of CI was 15 metabolic equivalents (METs)-hours/week (areas under the curve, 0.71; 95% confidence interval, 0.61?0.81; sensitivity, 71%; specificity, 69%). Conclusion: Our findings demonstrate that higher levels of PA are associated with a lower prevalence of CI, independent of potential confounders, and that 15 METs-hours/week of PA provides a cut-point for accurately predicting the presence of CI in adolescents with complex CHD.

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