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The Korean Organ Transplantation Registry (KOTRY): an overview and summary of the kidney-transplant cohort
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The Korean Organ Transplantation Registry (KOTRY): an overview and summary of the kidney-transplant cohort

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자료유형
학술저널
저자정보
전희정 (Hallym Kidney Research Institute Hallym University College of Medicine) 구태연 (성남시의료원) 주만기 (연세대학교) 채동완 (서울대학교) Soo Jin Na Choi (Chonnam National University) 김명수 (연세대학교) 유정화 (이화여자대학교) 정종철 (분당서울대학교병원) 안규리 (서울대학교) 양재석 (연세대학교)
저널정보
대한신장학회 Kidney Research and Clinical Practice Kidney Research and Clinical Practice Vol.41 No.4 KCI등재
발행연도
2022.7
수록면
492 - 507 (16page)
DOI
10.23876/j.krcp.21.185

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The Korean Organ Transplantation Registry (KOTRY): an overview and summary of the kidney-transplant cohort
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Background: As the need for a nationwide organ-transplant registry emerged, a prospective registry, the Korean Organ Transplantation Registry (KOTRY), was initiated in 2014. Here, we present baseline characteristics and outcomes of the kidney-transplant cohortfor 2014 through 2019. Methods: The KOTRY consists of five organ-transplant cohorts (kidney, liver, lung, heart, and pancreas). Data and samples were prospectively collected from transplant recipients and donors at baseline and follow-up visits; and epidemiological trends, allograft outcomes, and patient outcomes, such as posttransplant complications, comorbidities, and mortality, were analyzed. Results: From 2014 to 2019, there were a total of 6,129 registered kidney transplants (64.8% with living donors and 35.2% with deceased donors) with a mean recipient age of 49.4 ± 11.5 years, and 59.7% were male. ABO-incompatible transplants totaled 17.4%of all transplants, and 15.0% of transplants were preemptive. The overall 1- and 5-year patient survival rates were 98.4% and 95.8%,respectively, and the 1- and 5-year graft survival rates were 97.1% and 90.5%, respectively. During a mean follow-up of 3.8 years, biopsy-proven acute rejection episodes occurred in 17.0% of cases. The mean age of donors was 47.3 ± 12.9 years, and 52.6% weremale. Among living donors, the largest category of donors was spouses, while, among deceased donors, 31.2% were expanded-criteria donors. The mean serum creatinine concentrations of living donors were 0.78 ± 0.62 mg/dL and 1.09 ± 0.24 mg/dL at baselineand 1 year after kidney transplantation, respectively. Conclusion: The KOTRY, a systematic Korean transplant cohort, can serve as a valuable epidemiological database of Korean kidneytransplants.

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