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논문 기본 정보

자료유형
학술저널
저자정보
Song Ji Yeon (Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea) Lee Kyo Won (Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea) 김경아 (삼성서울병원) Kim Kyeong Deok (Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea) Yang Jaehun (Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea) Kwon Ji Eun (Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea) Lee Okjoo (Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea) Park Jae Berm (Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea)
저널정보
대한이식학회 Clinical Transplantation and Research Korean Journal of Transplantation Vol.35 No.4
발행연도
2021.12
수록면
238 - 246 (9page)
DOI
10.4285/kjt.21.0020

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Background: As a solution to organ shortages, studies on kidney transplantation (KT) from older donors are being conducted. However, many controversies remain about its safety and efficacy. Methods: In Samsung Medical Center, from January 2000 to May 2015, 1,141 patients underwent living KT. Cases of retransplantation, recipient and donor aged younger than 18 years, and multiorgan transplantation were excluded, and a total of 859 cases were selected. Analysis was performed by dividing the patents into two groups: a younger donor group (donors <60 years old; n=826) and an older donor group (donors ≥60 years old; n=33). Results: There were no significant differences between the two groups in patient death (log-rank P=0.173) or in postoperative complications. The older donor group had a higher acute rejection (P=0.034; hazard ratio [HR], 1.704) and graft failure rate (P=0.029, HR=2.352). There was no significant difference in the trend of estimated glomerular filtration rate over time (P=0.189). Conclusions: KT using kidneys from old-aged donors is safe, but there is room for improvement due to problems with higher acute rejection and graft failure rate.

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