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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 724 - 737 (14page)
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Background and Objectives: This second adult heart transplantation (HTx) report is based on Korean Organ Transplant Registry data submitted on 400 HTxs in recipients of all ages. Methods: From March 2014 to December 2017, a total of 400 HTxs were performed at 4 major centers in Korea. We analyzed demographics and characteristics according to transplant years. Patterns of immunosuppression, allograft rejection, and survival after HTx were analyzed. Donor and recipient age were highlighted. Results: Some distinct differences in HTx statistics were noted. Mean donor age increased significantly in the most recent years compared to 2014–2015, while mean recipient age did not change. The proportion of patients on pre-transplant extracorporeal membrane oxygenation (ECMO) increased over time. One-year and intermediate-term survival was significantly worse in patients on pre-transplant ECMO compared to those without mechanical support. Over the years, tacrolimus has increased to become the most frequently used calcineurin inhibitor over cyclosporine, while the number of patients using steroids both at discharge and 1-year follow-up has declined. Age did not affect 1-year survival, but significantly affected intermediate-term survival. Conclusions: From 2014 to 2017, centers were willing to accept older donors to address increasing organ shortages and more patients received transplant under ECMO care. Increasing age was a strong independent factor for intermediate-term survival, however, post-transplant comorbidities did not differ among age groups. Further studies with longer follow-up duration are needed to better understand age-related post-transplant prognosis.
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참고문헌 (17)
참고문헌 신청
김인철 / 2017 / Understanding the Current Status of Korean Heart Transplantation Based on Initial KOTRY Report / Korean Circulation Journal 47(6):858~860
김인철 / 2018 / The Past, Present and Future of Heart Transplantation / Korean Circulation Journal 48(7):565~590
Khush KK / 2018 / The international thoracic organ transplant registry of the International Society for Heart and Lung Transplantation : thirty-fifth adult heart transplantation report-2018; focus theme : multiorgan transplantation / J Heart Lung Transplant 37:1155~1168
이해영 / 2017 / Initial Report of the Korean Organ Transplant Registry (KOTRY): Heart Transplantation / Korean Circulation Journal 47(6):868~876
Viana LA / 2018 / Influence of epidemiology, immunosuppressive regimens, clinical presentation, and treatment on kidney transplant outcomes of patients diagnosed with tuberculosis : a retrospective cohort analysis / Am J Transplant
김인철 / 2018 / The Past, Present and Future of Heart Transplantation / Korean Circulation Journal 48(7):565~590
Khush KK / 2018 / The international thoracic organ transplant registry of the International Society for Heart and Lung Transplantation : thirty-fifth adult heart transplantation report-2018; focus theme : multiorgan transplantation / J Heart Lung Transplant 37:1155~1168
이해영 / 2017 / Initial Report of the Korean Organ Transplant Registry (KOTRY): Heart Transplantation / Korean Circulation Journal 47(6):868~876
Viana LA / 2018 / Influence of epidemiology, immunosuppressive regimens, clinical presentation, and treatment on kidney transplant outcomes of patients diagnosed with tuberculosis : a retrospective cohort analysis / Am J Transplant
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