지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.7
- 수록면
- 675 - 682 (8page)
- DOI
- 10.3349/ymj.2022.63.7.675
이용수
초록· 키워드
오류제보하기
Purpose: To identify initial abdominal computed tomography (CT) and laboratory findings prior to a diagnosis of Crohn’s disease(CD) in children.
Materials and Methods: In this retrospective study, patients (≤18 year-old) who were diagnosed with CD from 2004 to 2019 andhad abdominal CT just prior to being diagnosed with CD were included in the CD group. Patients (≤18 years old) who were diag nosed with infectious enterocolitis from 2018 to 2019 and had undergone CT prior to being diagnosed with enterocolitis were in cluded as a control group. We assessed the diagnostic performances of initial CT and laboratory findings for the diagnosis of CDusing logistic regression and the area under the curve (AUC).
Results: In total, 107 patients (50 CD patients, 57 control patients) were included, without an age difference between groups (me dian 13 years old vs. 11 years old, p=0.119). On univariate logistic regression analysis, multisegmental bowel involvement, mesen teric vessel engorgement, higher portal vein/aorta diameter ratio, longer liver longitudinal diameter, lower hemoglobin (≤12.5 g/dL), lower albumin (≤4 g/dL), and higher platelet (>320×103/μL) levels were significant factors for CD. On multivariate analysis,multisegmental bowel involvement [odds ratio (OR) 111.6, 95% confidence interval (CI) 4.778–2605.925] and lower albumin levels(OR 0.9, 95% CI 0.891–0.993) were significant factors. When these two features were combined, the AUC value was 0.985 with asensitivity of 96% and specificity of 100% for differentiating CD.
Conclusion: Multisegmental bowel involvement on CT and decreased albumin levels can help differentiate CD from infectiousenterocolitis in children prior to a definite diagnosis of CD.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Coexistence of Excessive Weight Gain and Celiac Disease in Children: An Unusual Familial Condition
Pediatric Gastroenterology, Hepatology & Nutrition
2019 .01
-
Leukemia propagating cells in Philadelphia chromosome-positive ALL: a resistant phenotype with an adverse prognosis
Blood Research
2018 .01
-
Extrinsic Acquisition of CD80 by Antigen-Specific CD8⁺ T Cells Regulates Their Recall Immune Responses to Acute Viral Infection
Immune Network
2019 .08
-
Comparison between Pediatric Crohn’s Disease and Ulcerative Colitis at Diagnosis in Korea: Results from a Multicenter, Registry-Based, Inception Cohort Study
Gut and Liver
2022 .11
-
CD5 Expression Dynamically Changes During the Differentiation of Human CD8+ T Cells Predicting Clinical Response to Immunotherapy
Immune Network
2023 .08
-
Changes in serum levels of lipopolysaccharides and CD26 in patients with Crohn’s disease
Intestinal research
2017 .01
-
Two Distinct Subsets Are Identified from the Peritoneal Myeloid Mononuclear Cells Expressing both CD11c and CD115
Immune Network
2019 .06
-
Korean clinical practice guidelines on biologics for moderate to severe Crohn’s disease
Intestinal research
2023 .01
-
Effect of Peripheral Blood CD4 + CD25 + Regulatory T Cell on Postoperative Immunotherapy for Patients with Renal Carcinoma
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Second Korean guidelines for the management of Crohn’s disease
Intestinal research
2017 .01
-
Immunogloboulin E-Mediated Food Sensitization in Children with Celiac Disease: A Single-Center Experience
Pediatric Gastroenterology, Hepatology & Nutrition
2021 .09
-
Effector Memory CD8+ and CD4+ T Cell Immunity Associated with Metabolic Syndrome in Obese Children
Pediatric Gastroenterology, Hepatology & Nutrition
2021 .01
-
Cluster Containing More Than 20 CD3-Positive Cells in Bone Marrow Biopsy Is a Candidate Prognostic Indicator in Peripheral T-Cell Lymphoma, Not Otherwise Specified
Annals of Laboratory Medicine
2019 .01
-
POEMS Syndrome: Bone Marrow, Laboratory, and Clinical Findings in 24 Korean Patients
Annals of Laboratory Medicine
2019 .01
-
Prognostic Implication of Semi-quantitative Immunohistochemical Assessment of CD20 Expression in Diffuse Large B-Cell Lymphoma
Journal of Pathology and Translational Medicine
2016 .01
-
The Role of CD4 T Cell Help in CD8 T Cell Differentiation and Function During Chronic Infection and Cancer
Immune Network
2023 .10
-
Changes in the Long-term Prognosis of Crohn’s Disease between 1986 and 2015: The Population-Based Songpa-Kangdong Inflammatory Bowel Disease Cohort Study
Gut and Liver
2022 .03
-
CD9 Expression in Colorectal Carcinomas and Its Prognostic Significance
Journal of Pathology and Translational Medicine
2016 .01
-
Prognostic Significance of CD109 Expression in Patients with Ovarian Epithelial Cancer
Journal of Pathology and Translational Medicine
2019 .01
-
Beyond the Role of CD55 as a Complement Component
Immune Network
2018 .02
이 논문의 저자 정보
최근 본 자료
댓글(0)
0