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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.3
- 수록면
- 133 - 142 (10page)
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초록· 키워드
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The locoregional recurrence rate after treatment of head and neck cancer (HNC) is known tobe about 40%, and recurrence of cancer is the major factor directly related to the survival ofpatients. Recurrent HNC has different biological characteristics and tumor microenvironmentfrom those of index cancer. And it subsequently exhibits pro-tumoral and treatment-resistanttraits, which leads to difficulties in selecting salvage treatments and followed by dismal prognosis.
Furthermore, since which salvage treatment can be selected and what the result of itwill be determined by the prior treatment, there should be careful consideration in the initialtherapeutic strategy. In this review, currently used treatment methods and results for locoregionallyrecurrent HNC are summarized, and considerations for each treatment based on theclinical and biomolecular characteristics of recurrent HNC are discussed. In addition, this reviewcontains introductions of new therapeutic strategies including recent clinical trials and aperspective on the future direction for treatment of locoregionally recurrent HNC.
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