지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.5
- 수록면
- 309 - 315 (7page)
- DOI
- https://doi.org/10.4111/icu.20210418
이용수
이 논문의 연구 히스토리 (2)
- 이 논문의 후속연구가 궁금하신가요?
- 연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
- 이 논문의 연구 히스토리 확인하기
초록· 키워드
오류제보하기
Purpose: We investigated the association between transient receptor potential vanilloid (TRPV) expression in human urothelium tissue and lower urinary tract dysfunction (LUTD).
Materials and Methods: We prospectively enrolled men who planned to undergo surgical treatment for benign prostatic obstruction to analyze TRPV1 and TRPV4 expression in the urothelium using enzyme-linked immunosorbent assay and immunofluorescence staining. Patients were divided into two groups based on urodynamics: the detrusor underactivity (DU) group and the non-DU group. Levels of TRPV1 and TRPV4 were compared between the two groups. We also divided patients into two groups according to degree of subjective urinary urgency symptoms using a 5-point urinary sensation scale and compared the differences in TRPV1 and TRPV4 levels between the two groups. The correlations between urodynamic parameters with TRPV1 or TRPV 4 in all patients were also analyzed.
Results: The levels of TRPV1 and TRPV 4 were not significantly different between the DU group (n=10) and the non-DU group (n=11). When we divided the patients according to degree of subjective urgency, the level of TRPV1 was not significantly different between the urgency group (n=10) and the non-urgency group (n =11), but the level of TRPV4 was significantly increased in the urgency group (p=0.029). There was no significant correlation between the level of TRPV1 or TRPV4 and urodynamic parameters in any patients.
Conclusions: TRPV4 could be a useful diagnostic biomarker for patients with LUTD.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Role of TRPV4 Channel in Human White Adipocytes Metabolic Activity
Endocrinology and Metabolism
2021 .10
-
Decreased Expression of TRPV4 Channels in HEI-OC1 Cells Induced by High Glucose Is Associated with Hearing Impairment
Yonsei Medical Journal
2018 .01
-
The Emerging Role of TRPV1 in Airway Inflammation
Allergy, Asthma & Immunology Research
2018 .01
-
Activation of transient receptor potential vanilloid 3 by the methanolic extract of Schisandra chinensis fruit and its chemical constituent γ-schisandrin
The Korean Journal of Physiology & Pharmacology
2017 .05
-
Neonatal Bladder Irritation Is Associated With Vanilloid Receptor TRPV1 Expression in Adult Rats
International Neurourology Journal
2018 .01
-
TRPV1 Blocking Alleviates Airway Inflammation and Remodeling in a Chronic Asthma Murine Model
Allergy, Asthma & Immunology Research
2018 .01
-
Expression of vesicular glutamate transporter in transient receptor potential vanilloid 1 (TRPV1)-positive neurons in the rat trigeminal ganglion
International Journal of Oral Biology
2021 .09
-
황금 추출물의 신경병증성 통증 유발 흰쥐에 미치는 영향
동의생리병리학회지
2018 .02
-
황금 추출물의 신경병증성 통증 유발 흰쥐에 미치는 영향
동의생리병리학회지
2018 .01
-
류마티스관절염 동물모델에서 관절염 치료에 따른 통증수용체의 발현
대한류마티스학회지
2015 .01
-
Study for the inhibition of transient receptor potential vanilloid type 1 by gomisin A
한국실험동물학회 학술발표대회 논문집
2021 .07
-
Ononis spinosa alleviated capsaicin-induced mechanical allodynia in a rat model through transient receptor potential vanilloid 1 modulation
The Korean Journal of Pain
2021 .01
-
Analgesic and anti-inflammatory effects of galangin: a potential pathway to inhibit transient receptor potential vanilloid 1 receptor activation
The Korean Journal of Pain
2024 .04
-
Antipruritic effect of curcumin on histamine-induced itching in mice
The Korean Journal of Physiology & Pharmacology
2018 .09
-
Combination of a Rapidly Penetrating Agonist and a Slowly Penetrating Antagonist Affords Agonist Action of Limited Duration at the Cellular Level
Biomolecules & Therapeutics(구 응용약물학회지)
2019 .01
-
The Influence of Glutaraldehyde Concentration on Electron Microscopic Multiple Immunostaining
International Journal of Oral Biology
2015 .01
-
The Effect of Low-Intensity Extracorporeal Shockwave Treatment on the Urinary Bladder in an Experimental Diabetic Rat Model
International Neurourology Journal
2021 .01
-
Olmsted Syndrome Caused by a Heterozygous p.Gly568Val Missense Mutation in TRPV3 Gene
Yonsei Medical Journal
2018 .01
-
Nootkatol prevents ultraviolet radiation-induced photoaging via ORAI1 and TRPV1 inhibition in melanocytes and keratinocytes
The Korean Journal of Physiology & Pharmacology
2021 .01
-
이중탕, 육군자탕, 보중익기탕의 이상지질혈증 및 고혈압과 관련된 일과성 수용체 전압 바닐로이드 4 이온통로 조절에 관한 연구
한방비만학회지
2018 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0