지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.4
- 수록면
- 1 - 7 (7page)
- DOI
- 10.1038/s12276-022-00752-w
이용수
초록· 키워드
오류제보하기
Cancer cachexia syndrome is a major cause of morbidity and mortality in cancer patients in the advanced stage. It is a devastating disorder characterized by nutritional impairment, weakness, and wasting, and it affects treatment success and quality of life. Two major symptoms of cancer cachexia are anorexia and weight loss. Weight loss in cachexia is not reversed through increased food intake, suggesting that anorexia and weight loss in cancer patients are regulated by independent molecular mechanisms. Although the wasting phenotype mostly occurs in skeletal muscle and adipose tissue, other organs, such as the brain, liver, pancreas, heart, and gut, are also involved in cachexia. Thus, cachexia is a multiorgan syndrome. Although the molecular basis of cancer cachexia-induced weight loss is known, the mechanism underlying anorexia is poorly understood. Here, we highlight our recent discovery of a new anorexia mechanism by which a tumor-derived humoral factor induces cancer anorexia by regulating feeding-related neuropeptide hormones in the brain. Furthermore, we elucidated the process through which anorexia precedes tissue wasting in cachexia. This review article aims to provide an overview of the key molecular mechanisms of anorexia and tissue wasting caused by cancer cachexia.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Pancreatic cancer induces muscle wasting by promoting the release of pancreatic adenocarcinoma upregulated factor
Experimental and Molecular Medicine
2021 .03
-
The contribution of the nervous system in the cancer progression
BMB Reports
2024 .04
-
3D printing of a patient-specific brain cancer-on-a-chip
대한기계학회 춘추학술대회
2017 .11
-
Analyzing Brain Cancer Survivability Using SEER(Surveillance, Epidemiology, and End Results Program) Data with method of Kaplan Meier
대한인간공학회 학술대회논문집
2015 .10
-
Microsensor for Cancer Detection and MEMS Actuator for Cancer Therapy
Transactions on Electrical and Electronic Materials
2023 .02
-
암 생존자의 질병관련 특성과 암 대처가 외상 후 성장에 미치는 영향
보건정보통계학회지
2015 .01
-
Gastrointestinal cancer organoids?applications in basic and translational cancer research
Experimental and Molecular Medicine
2021 .10
-
Assessment on spheroidal breast cancer models based on morphology, gene expression phenotype, and migratory phenotype
대한기계학회 춘추학술대회
2019 .04
-
3D printing of the patient-specific brain cancer-on-a-chip
대한기계학회 춘추학술대회
2017 .04
-
A Comprehensive study of colon cancer: using ML, DL and MIL techniques
한국정보통신학회 종합학술대회 논문집
2024 .05
-
Recent Advances in Electrochemical and Optical Biosensors for Cancer Biomarker Detection
BioChip Journal
2023 .03
-
ROS homeostasis and metabolism: a critical liaison for cancer therapy
Experimental and Molecular Medicine
2016 .01
-
Tumor Microenvironment Modulating Functional Nanoparticles for Effective Cancer Treatments
조직공학과 재생의학
2022 .04
-
The Awareness and Usage of Big Data for Cancer in Korea: A Survey Study
보건정보통계학회지
2021 .01
-
Biomaterials-based Cancer Vaccine Strategy for Precision Cancer Medicine
한국생물공학회 학술대회
2023 .04
-
Fabrication of Adipose Tissue-breast Cancer in Vitro Model by Controlling Distance to Adipose Tissue
한국정밀공학회 학술발표대회 논문집
2024 .11
-
The Use of Normal Stem Cells and Cancer Stem Cells for Potential Anti-Cancer Therapeutic Strategy
조직공학과 재생의학
2018 .01
-
A review on three dimensional scaffolds for tumor engineering
Biomaterials and Biomechanics in Bioengineering
2016 .01
-
Biomaterials-Based Cancer Vaccine Development for Precision Cancer Medicine
한국고분자학회 학술대회 연구논문 초록집
2023 .10
-
Identification of neuropeptide involved in cancer progression
한국생물공학회 학술대회
2015 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0