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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국광학회 Current Optics and Photonics Current Optics and Photonics Vol.1 No.1
발행연도
2017.2
수록면
17 - 22 (6page)

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초록· 키워드

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Mechanical property of tissue is closely related to diseases such as breast cancer, prostate cancer, cirrhosisof the liver, and atherosclerosis. Therefore measurement of tissue mechanical property is important for abetter diagnosis. Ultrasound elastography has been developed as a diagnostic modality for a number ofdiseases that maps mechanical property of tissue. Optical coherence elastography (OCE) has a higher spatialresolution than ultrasound elastography. OCE, therefore, could be a great help for early diagnosis. In thisstudy, we made tissue phantoms and measured their compressive moduli with a rheometer measuring theresponse to applied force. Uniaxial strain of the tissue phantom was also measured with OCE by usingcross-correlation of speckles and compared with the results from the rheometer. In order to comparestiffness of tissue phantoms by OCE, the applied force should be measured in addition to the strain. We,however, did not use a load cell that directly measures the applied force for each sample. Instead, weutilized one silicone film (called as reference phantom) for all OCE measurements that indirectly indicatedthe amount of the applied force by deformation. Therefore, all measurements were based on displacement,which was natural and effective for image-based elastography such as OCE.

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