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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 228 - 233 (6page)
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This research was carried out to investigate the moisturizing effects of Agarum cribrosum extract on normal human epidermal keratinocytes (NHEKs). Moisturizing effects of A. cribrosum extract on NHEKs were measured by quantitative realtime RT-PCR to verify the gene expressions related to skin hydration, hyaluronic acid (HA)-ELISA to detect HA production, and cell viability assays. A. cribrosum extract increased the mRNA levels of the AQP3 and HAS2 genes and HA production in NHEKs. On the other hand, A. cribrosum extract decreased the mRNA level of the KRT1 and KRT10 genes known as differentiated keratinocyte marker in NHEKs. This research showed the moisturizing effects of A. cribrosum extract. The results indicate that A. cribrosum extract can be a potent functional ingredient for skin hydration and anti-aging products. Further study is warranted regarding the use of A. cribrosum extract to develop not only cosmetics but also food and medicine.
목차
Abstract
재료 및 방법
결과 및 고찰
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참고문헌 (23)
참고문헌 신청
Assefa, Z. / 2005 / Ultraviolet radiation-induced apoptosis in keratinocytes : on the role of cytosolic factors / Biochimica et Biophysica Acta 1755:90~106
Fuchs, E. / 2007 / Scratching the surface of skin development / Nature 22:834~842
Fisher, G. J. / 2002 / Mechanisms of photoaging and chronological skin aging / Arch. Dermatol 138:1462~1470
Bickers, D. R. / 2006 / Oxidative stress in the pathogenesis of skin disease / J. Investig. Dermatol 126:256~275
Cao, C. / 2008 / All-trans retinoic acid attenuates ultraviolet radiation-induced down-regulation of aquaporin-3 and water permeability in human keratinocytes / J. Cell. Physiol 215:506~516
Fuchs, E. / 2007 / Scratching the surface of skin development / Nature 22:834~842
Fisher, G. J. / 2002 / Mechanisms of photoaging and chronological skin aging / Arch. Dermatol 138:1462~1470
Bickers, D. R. / 2006 / Oxidative stress in the pathogenesis of skin disease / J. Investig. Dermatol 126:256~275
Cao, C. / 2008 / All-trans retinoic acid attenuates ultraviolet radiation-induced down-regulation of aquaporin-3 and water permeability in human keratinocytes / J. Cell. Physiol 215:506~516
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