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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.3
- 수록면
- 33 - 39 (7page)
- DOI
- 10.20307/nps.2022.28.1.33
이용수
초록· 키워드
오류제보하기
Eight lignans (1-8) and two macrolides (9-10) were isolated from the CHCl₃-soluble fraction of Houttuynia cordata Thumb (Saururaceae). Structures of isolates were elucidated by extensive spectroscopic methods. Fatty acid-derived macrolides (9-10) have rarely been reported from nature. All the isolates were tested for their inhibitory activities against NO production in RAW 264.7 cells stimulated by LPS. It was found that compounds 3 and 9 remarkably down-regulated LPS-induced NO production with IC<SUB>50</SUB> values, 5.4 and 40.3 μM, respectively, without cytotoxicity.
목차
Abstract
Introduction
Experimental
Results and Discussion
References
참고문헌 (31)
참고문헌 신청
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Ahn, J.; Chae, H.-S.; Chin, Y.-W.; Kim, J. Bioorg. Med. Chem. Lett. 2017, 27, 2807-2811.
Bauer, R.; Pröbstle, A.; Lotter, H.; Wagner-Redecker, W.; Matthiesen, U. Phytomedicine 1996, 2, 305-308.
Kim, I. S.; Kim, J.-H.; Kim, J. S.; Yun, C.-Y.; Kim, D.-H.; Lee, J.-S. J. Ethnopharmacol. 2007, 112, 90-95.
Chen, S.-D.; Gao, H.; Zhu, Q.-C.; Wang, Y.-Q.; Li, T.; Mu, Z.-Q.; Wu, H .-L.; P eng, T.; Yao, X .-S. Org. Lett. 2012, 14, 1772-1775.
Ahn, J.; Chae, H.-S.; Chin, Y.-W.; Kim, J. Bioorg. Med. Chem. Lett. 2017, 27, 2807-2811.
Bauer, R.; Pröbstle, A.; Lotter, H.; Wagner-Redecker, W.; Matthiesen, U. Phytomedicine 1996, 2, 305-308.
Kim, I. S.; Kim, J.-H.; Kim, J. S.; Yun, C.-Y.; Kim, D.-H.; Lee, J.-S. J. Ethnopharmacol. 2007, 112, 90-95.
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