지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.9
- 수록면
- 175 - 182 (8page)
이용수
초록· 키워드
오류제보하기
This study evaluated the anti-Helicobacter and anti-inflammatory effects of Sohamhyungtang (SHHT). The minimum inhibitory concentration (MIC) of SHHT against Helicobacter pylori (H. pylori) was determined by the agar dilution method. Expression of the H. pylori cagA gene in the presence of SHHT was determined by quantitative real-time polymerase chain reaction (qRT-PCR). Inhibition of H. pylori urease by SHHT was determined by the phenol-hypochlorite assay. Antiadhesion activity of SHHT was measured by ureaphenol red reagent. Inhibition of nitric oxide (NO) production in AGS cells was measured with Griess reagent. Inducible nitric oxide synthase (iNOS) and IL-8 mRNA expression in AGS cells which were infected with H. pylori was determined by qRT-PCR. IL-8 level was measured by enzyme-linked immunosorbent assay (ELISA). The MIC of SHHT was 100 μg/mL and the expression of cagA gene was decreased about 25 folds in the presence of SHHT. H. pylori urease was inhibited 90% by SHHT. SHHT inhibited H. pylori adhesion on AGS cell in a concentration dependent manner. mRNA expression of iNOS and IL-8 and the production of NO and IL-8 were significantly decreased in the presence of SHHT. In conclusion, SHHT showed anti-Helicobacter activity and has potent anti-inflammatory effect on H. pylori-induced inflammation in human gastric epithelial AGS cells.
목차
등록된 정보가 없습니다.
참고문헌 (32)
참고문헌 신청
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
백지(Angelica dahurica) 추출물의 Helicobacter pylori에 대한 항균력 및 H. pylori로 유도한 염증반응에 대한 항염 효과
생약학회지(Korean Journal of Pharmacognosy)
2018 .09
-
Regulation in the Expression of Virulence Factors of Helicobacter pylori by the Interaction between AGS Cells and H. pylori
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2022 .12
-
Steamed Ginger Extract Exerts Anti-inflammatory Effects in Helicobacter pylori-infected Gastric Epithelial Cells through Inhibition of NF-κB
대한암예방학회지
2021 .12
-
Anti-microbial and anti-inflammatory effects of Cheonwangbosim-dan against Helicobacter pylori-induced gastritis
Journal of Veterinary Science
2020 .05
-
Association between Helicobacter pylori and Gastric Cancers
Gut and Liver
2017 .01
-
Helicobacter pylori 백신 개발 현황과 전망
Korean Journal of Helicobacter Upper Gastrointestinal Research
2016 .01
-
국내 Helicobacter pylori 감염의 유병률 변화와 향후 과제
Korean Journal of Helicobacter Upper Gastrointestinal Research
2016 .01
-
Helicobacter pylori 제균 치료가 위암을 예방할 수 있는가?
Korean Journal of Helicobacter Upper Gastrointestinal Research
2016 .01
-
Inhibition of Helicobacter pylori-induced inflammation in human gastric epithelial AGS cells by the fruits of Tribulus terrestris L. extracts
Journal of Biomedical and Translational Research
2017 .09
-
In Vitro Activity of Diphenyleneiodonium toward Multidrug-Resistant Helicobacter pylori Strains
Gut and Liver
2017 .01
-
Must-Have Knowledge about the Helicobacter pylori-Negative Gastric Cancer
Gut and Liver
2016 .01
-
Helicobacter pylori Infection with Atrophic Gastritis Is an Independent Risk Factor for Advanced Colonic Neoplasm
Gut and Liver
2016 .01
-
IL-17A promotes Helicobacter pylori-induced gastric carcinogenesis via interactions with IL-17RC
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Helicobacter pylori 음성 위암
Korean Journal of Helicobacter Upper Gastrointestinal Research
2021 .01
-
Diphenyleneiodonium Inhibits Apoptotic Cell Death of Gastric Epithelial Cells Infected with Helicobacter pylori in a Korean Isolate
Yonsei Medical Journal
2015 .01
-
Astaxanthin Prevents Decreases in Superoxide Dismutase 2 Level and Superoxide Dismutase Activity in Helicobacter pylori-infected Gastric Epithelial Cells
대한암예방학회지
2019 .01
-
[CORRECTION] Changes in Helicobacter pylori Immunoglobulin G Levels and Gastric Mucosal Atrophy after Successful Eradication of Helicobacter pylori
Korean Journal of Helicobacter Upper Gastrointestinal Research
2019 .01
-
Serum 8 Hydroxydeoxyguanosine and Cytotoxin Associated Gene A as Markers for Helicobacter pylori Infection
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
헬리코박터 파일로리 감염의 역학과 병태생리
대한내과학회지
2015 .01
-
Postoperative Helicobacter pylori Infection as a Prognostic Factor for Gastric Cancer Patients after Curative Resection
Gut and Liver
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2023-518-000051820