메뉴 건너뛰기
Library Notice
Institutional Access
If you certify, you can access the articles for free.
Check out your institutions.
ex)Hankuk University, Nuri Motors
Log in Register Help KOR
Subject
Humanities
General Humanities History Philosophy Religious Studies Linguistics and Literature Other Humanities
Social science
General Social Science Business Management Tourism Education Military Science Library and Information Science Law Sociology Journalism and Media Studies Psychological Science Political Science and Diplomacy Geography Public Administration Economics International Trade Anthropology Other Social Science
Natural science
General Natural Science Physics Biology Life Sciences Mathematics/Statistics Astronomy Earth Science Chemistry Other Natural Science
Engineering
General Engineering Architectural Engineering Mechanical Engineering Industrial Engineering Material/Energy Engineering Electrical and Electronic Engineering Marine and Ocean Engineering Chemical Engineering Computer Science Other Engineering
Medical science
General Medical Science Nursing Science Veterinary Pharmacy Traditional Korean Medicine Basic Medicine Clinical Medicine Other Medicine
Agriculture and Fishery
General Agriculture and Fishery Agriculture Fishery Science Food Science Forestry Animal Husbandry Marine Transportation Studies Other Agriculture and Fishery
Art and Kinesiology
General Arts Design Fine Arts Cosmetology Photography Music Fashion Kinesiology Performing Media Arts Other Arts and Kinesiology
Interdisciplinary Studies
Interdisciplinary Research Science and Technology Studies Brain and Cognitive Science Technology Policy Other Interdisciplinary Studies

KOR

Quantitative Determination of the Bioactive Marker Components in Gyeji-tang Using LC-ESI-MS/MS
Recommendations
Search
Questions

LC-ESI-MS/MS를 이용한 계지탕 중 주요 성분 분석

논문 기본 정보

Type
Academic journal
Author
Journal
Korean Society of Phamacognosy 생약학회지(Korean Journal of Pharmacognosy) Vol.49 No.1 KCI Accredited Journals SCOPUS
Published
2018.3
Pages
76 - 83 (8page)

Usage

cover
📌
Topic
📖
Background
🔬
Method
🏆
Result
Quantitative Determination of the Bioactive Marker Components in Gyeji-tang Using LC-ESI-MS/MS
Ask AI
Recommendations
Search
Questions

Abstract· Keywords

Report Errors
A traditional herbal formula, Gyeji-tang has been used to treat the early colds, headache, chills, and fever in Asian countries. In this study, we were performed simultaneous determination of the 14 bioactive marker compounds, gallic acid, spinosin, paeoniflorin, albiflorin, liquiritin apioside, liquiritin, 6′′′-feruloylspinosin, liquilitigenin, coumarin, cinnmamic acid, benzoylpaeoniflorin, cinnamaldehyde, glycyrrhizin, and 6-gingerol in Gyeji-tang using an ultra-performance liquid chromatography- electrospray ionization-mass spectrometry (UPLC-ESI-MS/MS). Analytical column was used a Waters Acquity UPLC BEH C<sub>18</sub> analytical column (2.1×100 mm, 1.7 μm) and maintained at 45 o C with a flow rate of 0.3 mL/min. The mobile phase consists of 0.1% (v/v) formic acid in water and acetonitrile with gradient elution. The MS analysis was conducted using multiple reaction monitoring in the positive and negative modes by a Waters ACQUITY TQD LC-MS/MS system. The calibration curves of 14 bioactive marker compounds showed linearity with correlation coefficients ≥ 0.9798. The limits of detection and quantification values were in the range of 0.11-6.66 ng/mL and 0.34-19.99 ng/mL, respectively. As a result of the analysis using the established LC-MS/MS method, the amounts of tested 14 compounds in the lyophilized Gyeji-tang sample were detected up to 85.7 μg/g. These results may be useful for quality assessment of a traditional herbal formulas.
#Gyeji-tang #LC-ESI-MS/MS #Quantitative determination

Contents

No content found

References (26)

Add References
이승준 / 2012 / 상한론의 ‘其氣上衝’과 ‘桂枝湯’에 대한 연구 / 대한한의학 방제학회지 20(2):165~176 google schola Heo, J. / 2004 / Donguibogam / Namsandang :380 google schola Yoo, S. R. / 2016 / Gyeji-tang water extract exerts anti-inflammatory activity through inhibition of ERK and NF-${\kappa}B$ pathways in lipopolysaccharide-stimulated RAW 264.7 cells / BMC Complement. Altern. Med. 16:390~399 Crossref Jiao, H. / 2012 / Effects of guizhi tang on inflammatory cytokines in myocardial ischemia and hyperlipidemia rats / Zhongguo Zhong Yao Za Zhi 37:1634~1637 google schola Kutsuwa, M. / 1998 / A comparative study of Kakkon-to and Keishi-to on prostaglandin E(2) release from rabbit astrocytes / Phymedicine 5:275~282 google schola

Recommendations

It is an article recommended by DBpia according to the article similarity. Check out the related articles!

Related Authors

Recently viewed articles

Literary Didactics and Literary History
Ra, Young-kyunInstitute of Foreign Literature2022.05
 법성종의 입장에서 바라본 정토사상
GYOO TAG SHIN2010
 How are conceptual metaphors expressed in different languages?
Zoltan KovecsesThe Discourse and Cognitive Linguistics Society of Korea2003.06
 대중교통 이용 예측도 인공지능(AI) 기술이 필요한 시대
김병관, 김채만, 박지선Gyeonggi Research Institute2021.12

Comments(0)

0

Write first comments.

UCI(KEPA) : I410-ECN-0101-2023-518-000070521