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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.3
- 수록면
- 15 - 22 (8page)
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초록· 키워드
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The aim of this study was to develop a UPLC method for simultaneous analysis of 8 phenolic compounds including gallic aicd (1), protocatechuic acid (2), methyl gallate (3), ellagic acid (4), kaempferol-3-arabinofranosyl-7-rhamnoside (5), kaempferitrin (6), afzelin (7) and kaempferol-7-rhamnoside (8) isolated from Geranium thunbergii which has been traditionally used as anti-diarrheal agent. The UPLC method was optimized and validated using Halo C18 column (4.6×100 mm, 2.7 μm) consisting of MeOH and 0.1% formic acid at 260 nm in 25 minutes. In quantitative analysis of 8 compounds in MeOH extract of G. thunbergii, contents of 4-6 were 12.39, 20.52 and 21.45 mg/g, respectively. These compounds were measured as major phenolic compounds in G. thunbergii and can be useful as marker compounds for its quality control. These results suggest that the UPLC method can be contributed as basic data for quality evaluation of herbal preparations.
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참고문헌 (17)
참고문헌 신청
성미선 / 2014 / 가시오가피를 이용한 기능성 건강음료의 제조 / 생명과학회지 24(9):959~966
Qing-He Liu / 2006 / A New Furofuran Lignan from Geranium thunbergii Sieb. et Zucc. / Archives of Pharmacal Research 29(12):1109~1113
Pokharel, Y. R. / 2007 / 4-Hydroxy-kobusin inhibits the induction of nitric oxide synthase by inhibiting NF-kappaB and AP-1 activation / Biol. Pharm. Bull. 30:1097~1101
Takuo, O. / 1975 / Brevifolin, corilagin and other phenols from Geranium thunbergii / Phytochemistry 14:1877~1878
Takuo, O. / 1979 / Constituents of Geranium thunbergii Sieb. et Zucc.: VII. High-Performance reversed-phase liquid chromatography of hydrolysable tannins and related polyphenols / J. Chromatogr. A. 171:313~320
Qing-He Liu / 2006 / A New Furofuran Lignan from Geranium thunbergii Sieb. et Zucc. / Archives of Pharmacal Research 29(12):1109~1113
Pokharel, Y. R. / 2007 / 4-Hydroxy-kobusin inhibits the induction of nitric oxide synthase by inhibiting NF-kappaB and AP-1 activation / Biol. Pharm. Bull. 30:1097~1101
Takuo, O. / 1975 / Brevifolin, corilagin and other phenols from Geranium thunbergii / Phytochemistry 14:1877~1878
Takuo, O. / 1979 / Constituents of Geranium thunbergii Sieb. et Zucc.: VII. High-Performance reversed-phase liquid chromatography of hydrolysable tannins and related polyphenols / J. Chromatogr. A. 171:313~320
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