지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.3
- 수록면
- 38 - 42 (5page)
이용수
초록· 키워드
오류제보하기
Caragana sinica (Leguminosae) is a plant, which has been used as a traditional medicine for the treatment of lots of diseases including neuralgia, goat, hypertension and eczema. However, scientific studies of C. sinica in pharmacological aspects are not carried out. In this study, the anti-nociceptice effect of methanolic extract of C. sinica (MCS) was evaluated using various pain models. Our data represented that MCS significantly delayed the latency time under central pain condition which are arose from thermal stimuli, indicating MCS possess analgesic potential against central nociception. In addition, MCS showed strong and dose-dependent anti-nociceptive activities on acetic acid-induced peripheral pain, compared to positive control such as indomethacin. Further combination studies using naloxone, a non-selective opioid receptor antagonist, have revealed that analgesic activity of MCS was not changed in the presence of naloxone, indicating MCS exerts anti-nociceptive activity independent of opioid receptor. These results suggest that MCS may be an effective medicine in managing pain.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Jin, Q. / 2012 / Antioxidative oligostilbenes from Caragana sinica / Bioorg. Med. Chem. Lett. 22:973~976
Xiao, L. P. / 2011 / Structural characterization of lignins isolated from Caragana sinica using FT-IR and NMR spectroscopy / Guang Pu Xue Yu Guang Pu Fen Xi 31:2369~2376
Lee, S. R. / 2014 / Kobophenol A inhibits sodium nitroprusside-induced cardiac H9c2 cell death through suppressing activation of JNK and preserving mitochondrial anti-apoptotic Bcl-2 and Mcl-1 / Chem. Pharm. Bull. 62:713~718
Bonica, J. J. / 1979 / The need of a taxonomy / Pain 6:247~248
Holden, A. V. / 1984 / The neurobiology of pain: symposium of the northern neurobiology group, Held at leeds on 18 April, 1983 / Manchester University Press
Xiao, L. P. / 2011 / Structural characterization of lignins isolated from Caragana sinica using FT-IR and NMR spectroscopy / Guang Pu Xue Yu Guang Pu Fen Xi 31:2369~2376
Lee, S. R. / 2014 / Kobophenol A inhibits sodium nitroprusside-induced cardiac H9c2 cell death through suppressing activation of JNK and preserving mitochondrial anti-apoptotic Bcl-2 and Mcl-1 / Chem. Pharm. Bull. 62:713~718
Bonica, J. J. / 1979 / The need of a taxonomy / Pain 6:247~248
Holden, A. V. / 1984 / The neurobiology of pain: symposium of the northern neurobiology group, Held at leeds on 18 April, 1983 / Manchester University Press
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
팥배나무의 진통 효과
생약학회지(Korean Journal of Pharmacognosy)
2020 .09
-
Effects of medical communication curriculum on perceptions of Korean medical school students
Korean Journal of Medical Education
2018 .01
-
히어리의 鎭痛 效能
생약학회지(Korean Journal of Pharmacognosy)
2019 .12
-
Surface characteristics and bioactivity of minocycline-treated Ti-6Al-4V alloy
Oral Biology Research
2018 .01
-
Prognostic Value in Preoperative Veterans RAND-12 Mental Component Score on Clinical Outcomes for Patients Undergoing Minimally Invasive Lateral Lumbar Interbody Fusion
Neurospine
2024 .03
-
Anti-nociceptive and anti-inflammatory activities of the essential oil isolated from Cupressus arizonica Greene fruits
The Korean Journal of Pain
2022 .01
-
Ginsenoside compound-Mc1 attenuates oxidative stress and apoptosis in cardiomyocytes through an AMP-activated protein kinase-dependent mechanism
Journal of Ginseng Research
2020 .07
-
Mindray MC-80 자동디지털세포형태분석기와 수동 검사법 비교: 말초혈액 도말의 비정상 세포 분석
Laboratory Medicine Online
2024 .07
-
누리장나무의 진통 효과
생약학회지(Korean Journal of Pharmacognosy)
2023 .06
-
All about pain pharmacology: what pain physicians should know
The Korean Journal of Pain
2020 .01
-
의학의 관점에서 본 포경수술의 가치
대한의사협회지
2016 .01
-
감태나무 에틸아세테이트 분획의 항염증 및 진통 효과
생약학회지(Korean Journal of Pharmacognosy)
2022 .03
-
Current understanding of nociplastic pain
The Korean Journal of Pain
2024 .04
-
Determination of potassium isotopes using collision cell MC-ICP-MS
환경독성보건학회 심포지엄 및 학술대회
2019 .10
-
Melanocortin 4 Receptor and Dopamine D2 Receptor Expression in Brain Areas Involved in Food Intake
Endocrinology and Metabolism
2015 .01
-
수년간 지속된 요통을 호소하는 22세 여자
대한내과학회지
2023 .04
-
Effects of Selenium nanoparticles on bone differentiation of MC3T3-E1 cells at high reactive oxygen species concentrations
대한치과재료학회 학술대회
2020 .10
-
Anti-nociceptive and Anti-inflammatory Effect of an Ethanol Extract Mixture of Vitis amurensis, Aralia cordata, and Glycyrrhizae radix
Journal of Biomedical and Translational Research
2017 .06
-
Drug use evaluation of opioid analgesics in pain management among patients with hematopoietic stem cell transplantation
Blood Research
2020 .01
-
Anti-obesity effect of micro-current stimulation by activating Wnt/β-Catenin signaling in ob/ob mice model
한국실험동물학회 학술발표대회 논문집
2021 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2023-518-000069359