지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Different ligands can lead to the activation of epidermal growth factor receptor, and the subsequent signal transduction leads to an increase in cellular motility, proliferation, invasion, and blocking of apoptosis, and all of this contributes to the development and progression of cancer. Our studies clarified; 1) The EGFR expression level is reduced during tumor progression or during ligand-induced EGFR activation. 2) ANXA8 and its regulatory pathway may well be alternative, strategic targets for inhibiting tumor metastasis. 3) The molecular pathway of EphA2 signaling and provide insight into the mechanisms that control cancer progression and metastatic spread in cholangiocarcinoma (CC). Therefore, therapeutic strategies that target EphA2 and its downstream effectors may be useful to control CC.
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등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
Mittal B / 1985 / Primary cancers of extrahepatic biliary passages / Int J Radiat Oncol Biol Phys 11:849~854
Pitt HA / 1995 / Perihilar cholangiocarcinoma. Postoperative radiotherapy does not improve survival / Ann Surg 221:788~797
Vauthey JN / 1994 / Blumgart LH : Recent advances in the management of cholangiocarcinomas / Semin Liver Dis 14:109~114
Jarnagin WR / 2001 / Staging, resectability, and outcome in 225 patients with hilar cholangiocarcinoma / Ann. Surg 234:507~517
Yoon JH / 2004 / Enhanced epidermal growth factor receptor activation in human cholangiocarcinoma cells / J Hepatol 41:808~814
Pitt HA / 1995 / Perihilar cholangiocarcinoma. Postoperative radiotherapy does not improve survival / Ann Surg 221:788~797
Vauthey JN / 1994 / Blumgart LH : Recent advances in the management of cholangiocarcinomas / Semin Liver Dis 14:109~114
Jarnagin WR / 2001 / Staging, resectability, and outcome in 225 patients with hilar cholangiocarcinoma / Ann. Surg 234:507~517
Yoon JH / 2004 / Enhanced epidermal growth factor receptor activation in human cholangiocarcinoma cells / J Hepatol 41:808~814
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