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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 235 - 242 (8page)
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Purpose: This study aimed to identify the risk factors for surgical site infections (SSIs) in patients undergoing colorectal cancer surgery and to determine whether significantly different SSI rates existed between the short prophylactic antibiotic use group (within 24 hours) and the long prophylactic antibiotic use group (beyond 24 hours). Methods: The medical records of 327 patients who underwent colorectal resection due to colorectal cancer from January 2010 to May 2014 at a single center were retrospectively reviewed, and their characteristics as well as the surgical factors known to be risk factors for SSIs, were identified. Results: Among the 327 patients, 45 patients (13.8%) developed SSIs. The patients were divided into two groups according to the duration of antibiotic use: group S (within 24 hours) and group L (beyond 24 hours). Of the 327 patients, 114 (34.9%) were in group S, and 213 (65.1%) were in group L. Twelve patients (10.5%) in group S developed SSIs while 33 patients (15.5%) in group L developed SSIs (P = 0.242). History of diabetes mellitus and lung disease, long operation time, and perioperative transfusion were independent risk factors for SSIs. Conclusion: This study shows that discontinuation of prophylactic antibiotics within 24 hours after colorectal surgery has no significant influence on the incidence of SSIs. This study also showed that history of diabetes mellitus and lung disease, long operation time, and perioperative transfusion were associated with increased SSI rates.
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참고문헌 (30)
참고문헌 신청
Jarvis WR / 1996 / Selected aspects of the socioeconomic impact of nosocomial infections: morbidity, mortality, cost, and prevention / Infect Control Hosp Epidemiol 17:552~557
Leaper DJ / 2004 / Surgical site infection - a European perspective of incidence and economic burden / Int Wound J 1:247~273
Gorbach SL / 1992 / Evaluation of new anti-infective drugs for surgical prophylaxis. Infectious Diseases Society of America and the Food and Drug Administration / Clin Infect Dis 15(Suppl 1):S313~S338
Bratzler DW / 2013 / Clinical practice guidelines for antimicrobial prophylaxis in surgery / Am J Health Syst Pharm 70:195~283
Burton RC / 1973 / Postoperative wound infection in colonic and rectal surgery / Br J Surg 60:363~365
Leaper DJ / 2004 / Surgical site infection - a European perspective of incidence and economic burden / Int Wound J 1:247~273
Gorbach SL / 1992 / Evaluation of new anti-infective drugs for surgical prophylaxis. Infectious Diseases Society of America and the Food and Drug Administration / Clin Infect Dis 15(Suppl 1):S313~S338
Bratzler DW / 2013 / Clinical practice guidelines for antimicrobial prophylaxis in surgery / Am J Health Syst Pharm 70:195~283
Burton RC / 1973 / Postoperative wound infection in colonic and rectal surgery / Br J Surg 60:363~365
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