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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 172 - 176 (5page)
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Purpose: This study evaluated the effectiveness of prophylactic antibiotics in elective laparoscopic cholecystectomy (LCC) for thereduction of postoperative infection rate. Materials and Methods: Elective LCC was performed on 529 patients at Jeonbuk National University Hospital between April 2015and August 2017. A total of 509 patients were enrolled based on the inclusion criteria. This prospective study compared the resultsfor antibiotic group (AG) (n=249, cefotetan 1 g, 1 dose/prophylactic) and non-antibiotic group (NAG) (n=260). Results: There were no significant differences in clinical characteristics between the two groups: AG and NAG (p=0.580, 0.782, and0.325, respectively). Levels of C-reactive protein were higher in NAG compared to AG at postoperative day 2 (16.6±24.2 vs. 24.2±40.6; p=0.033). There were no significant differences in white blood cell counts and erythrocyte sedimentation rate. Fever≥38°C on postoperative day 2 occurred in 3 (1.2%) and 9 (3%) patients in AG and NAG, respectively. One patient in each grouphad subhepatic fluid collection by abdominal computed tomography, but there was no evidence of infection. Two patients inNAG (3%) had serous wound drainage on postoperative day 14. Conclusion: Our results showed no significant differences in patients receiving or not receiving prophylactic antibiotics duringLCC. Therefore, it is not necessary to use prophylactic antibiotics during elective LCC in patients who meet the inclusion criteria.
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참고문헌 (17)
참고문헌 신청
McGuckin M / 1999 / Infection and antimicrobial use in laparoscopic cholecystectomy / Infect Control Hosp Epidemiol 20:624~626
Catarci M / 2004 / Antibiotic prophylaxis in elective laparoscopic cholecystectomy. Lack of need or lack of evidence? / Surg Endosc 18:638~641
Choudhary A / 2008 / Role of prophylactic antibiotics in laparoscopic cholecystectomy : a metaanalysis / J Gastrointest Surg 12:1847~1853
Zhou H / 2009 / Meta-analysis : antibiotic prophylaxis in elective laparoscopic cholecystectomy / Aliment Pharmacol Ther 29:1086~1095
Sanabria A / 2010 / Antibiotic prophylaxis for patients undergoing elective laparoscopic cholecystectomy / Cochrane Database Syst Rev :CD005265
Catarci M / 2004 / Antibiotic prophylaxis in elective laparoscopic cholecystectomy. Lack of need or lack of evidence? / Surg Endosc 18:638~641
Choudhary A / 2008 / Role of prophylactic antibiotics in laparoscopic cholecystectomy : a metaanalysis / J Gastrointest Surg 12:1847~1853
Zhou H / 2009 / Meta-analysis : antibiotic prophylaxis in elective laparoscopic cholecystectomy / Aliment Pharmacol Ther 29:1086~1095
Sanabria A / 2010 / Antibiotic prophylaxis for patients undergoing elective laparoscopic cholecystectomy / Cochrane Database Syst Rev :CD005265
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