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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한백신학회 Clinical and Experimental Vaccine Research Clinical and Experimental Vaccine Research Vol.7 No.1
- 발행연도
- 2018.1
- 수록면
- 82 - 86 (5page)
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초록· 키워드
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To develop the large scale serological assay for severe fever with thrombocytopenia syndrome virus (SFTSV) infection, we evaluated two different enzyme-linked immunosorbent assay (ELISA) methods using nucleocapsid protein (NP) and Gn proteins of CB1 (genotype B) SFTSV strains. The NP-based ELISA tests showed more sensitive with broad cross-reactivity between two different genotype A and B strains compared with those of Gn-based ELISA tests. However, Gn-based ELISA showed more genotype specificity and specificity. These result suggested that NP-based ELISA test could be applicable for general sero-prevalence studies of SFTSV infections, while Gn-based ELISA could be applicable for a certain specific genotype sero-prevalence study.
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참고문헌 (19)
참고문헌 신청
Jin C / 2012 / Pathogenesis of emerging severe fever with thrombocytopenia syndrome virus in C57/ BL6 mouse model / Proc Natl Acad Sci U S A 109:10053~10058
Liu S / 2014 / Systematic review of severe fever with thrombocytopenia syndrome: virology, epidemiology, and clinical characteristics / Rev Med Virol 24:90~102
Yu XJ / 2011 / Fever with thrombocytopenia associated with a novel bunyavirus in China / N Engl J Med 364:1523~1532
Takahashi T / 2014 / The first identification and retrospective study of severe fever with thrombocytopenia syndrome in Japan / J Infect Dis 209:816~827
Kim KH / 2013 / Severe fever with thrombocytopenia syndrome, South Korea, 2012 / Emerg Infect Dis 19:1892~1894
Liu S / 2014 / Systematic review of severe fever with thrombocytopenia syndrome: virology, epidemiology, and clinical characteristics / Rev Med Virol 24:90~102
Yu XJ / 2011 / Fever with thrombocytopenia associated with a novel bunyavirus in China / N Engl J Med 364:1523~1532
Takahashi T / 2014 / The first identification and retrospective study of severe fever with thrombocytopenia syndrome in Japan / J Infect Dis 209:816~827
Kim KH / 2013 / Severe fever with thrombocytopenia syndrome, South Korea, 2012 / Emerg Infect Dis 19:1892~1894
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