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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 질병관리본부 Osong Public Health and Research Persptectives Osong Public Health and Research Persptectives Vol.8 No.1
- 발행연도
- 2017.1
- 수록면
- 47 - 53 (7page)
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Objectives: Integrons are thought to play an important role in the spread of antibiotic resistance. This study investigates class 1 and 2 integron-positive methicillin-resistant coagulase-negative staphylococci strains isolated in Iran and characterizes their patterns of antimicrobial resistance. Methods: Hundred clinical isolates of coagulase-negative staphylococci were characterized for integron content and staphylococcal cassette chromosome mec (SCCmec) type. Results: Sixteen isolates carried class 1 (intI1) integrons and four isolates carried class 2 (intI2) integrons. One resistance gene array was identified among the class 1 integrons (aadA1 cassette). The distribution of SCCmec types in 50 methicillin-resistant coagulase-negative staphylococci strains showed that SCCmec types III and V dominated among the tested strains. Conclusion: This is the first report of methicillin-resistant coagulase-negative staphylococci strains that carry two mobile genetic elements, including class 1 and 2 integrons and SCCmec, in Iran.
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참고문헌 (36)
참고문헌 신청
R. Ben-Ami / 2003 / Infection of a Ventriculoatrial Shunt with Phenotypically Variable Staphylococcus epidermidis Masquerading as Polymicrobial Bacteremia Due to Various Coagulase-Negative Staphylococci and Kocuria varians / Journal of Clinical Microbiology 41(6):2444~2447
Nouwen JL / 1998 / Clonal expansion of Staphylococcus epidermidis strains causing Hickman catheter-related infections in a hemato-oncologic department / J Clin Microbiol 36:2696~2702
Gordon L. Archer / 1994 / Origin and evolution of DNA associated with resistance to methicillin in staphylococci / Trends in Microbiology 2(10):343~347
Y. Katayama / 2000 / A New Class of Genetic Element, Staphylococcus Cassette Chromosome mec, Encodes Methicillin Resistance in Staphylococcus aureus / Antimicrobial Agents and Chemotherapy 44(6):1549~1555
K. Zhang / 2005 / Novel Multiplex PCR Assay for Characterization and Concomitant Subtyping of Staphylococcal Cassette Chromosome mec Types I to V in Methicillin-Resistant Staphylococcus aureus / Journal of Clinical Microbiology 43(10):5026~5033
Nouwen JL / 1998 / Clonal expansion of Staphylococcus epidermidis strains causing Hickman catheter-related infections in a hemato-oncologic department / J Clin Microbiol 36:2696~2702
Gordon L. Archer / 1994 / Origin and evolution of DNA associated with resistance to methicillin in staphylococci / Trends in Microbiology 2(10):343~347
Y. Katayama / 2000 / A New Class of Genetic Element, Staphylococcus Cassette Chromosome mec, Encodes Methicillin Resistance in Staphylococcus aureus / Antimicrobial Agents and Chemotherapy 44(6):1549~1555
K. Zhang / 2005 / Novel Multiplex PCR Assay for Characterization and Concomitant Subtyping of Staphylococcal Cassette Chromosome mec Types I to V in Methicillin-Resistant Staphylococcus aureus / Journal of Clinical Microbiology 43(10):5026~5033
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