지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 17 - 21 (5page)
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초록· 키워드
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Background and Objectives: The aim of this study was to investigate serum paraoxanase-1 (PON) activity, total oxidant status (TOS), total antioxidant status (TAS), and the oxidative stress index (OSI) in tinnitus; and to compare the results with data from healthy subjects. Subjects and Methods: A total of 114 subjects-54 patients with tinnitus and 60 healthy controls were enrolled in this study. Serum PON activity, TOS, TAS, and OSI levels were measured. Results: In the tinnitus group, TAS, and PON were significantly lower than in the control group (p<0.001). However, the TOS, and OSI levels were significantly higher in the tinnitus group than in the control group (p<0.001). Conclusions: According to the data obtained from the present study, patients with tinnitus were exposed to potent oxidative stress. Oxidative stress may be the key contributing factor to the pathogenesis of tinnitus.
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참고문헌 (29)
참고문헌 신청
Jufas NE / 2015 / The use of benzodiazepines for tinnitus: systematic review / J Laryngol Otol 129(Suppl 3):S14~S22
Nemholt SS / 2015 / Prevalence of tinnitus and/or hyperacusis in children and adolescents: study protocol for a systematic review / BMJ Open 5:e006649
이재희 / 2014 / Adequacy of the Simplified Version of the Tinnitus Handicap Inventory (THI-S) to Measure Tinnitus Handicap and Relevant Distress / Journal of Audiology & Otology 18(1):19~27
Karatas E / 2012 / The comparison of acoustic and psychic parameters of subjective tinnitus / Eur Arch Otorhinolaryngol 269:441~447
Calabrese V / 2010 / Oxidative stress, redox homeostasis and cellular stress response in Ménière’s disease: role of vitagenes / Neurochem Res 35:2208~2217
Nemholt SS / 2015 / Prevalence of tinnitus and/or hyperacusis in children and adolescents: study protocol for a systematic review / BMJ Open 5:e006649
이재희 / 2014 / Adequacy of the Simplified Version of the Tinnitus Handicap Inventory (THI-S) to Measure Tinnitus Handicap and Relevant Distress / Journal of Audiology & Otology 18(1):19~27
Karatas E / 2012 / The comparison of acoustic and psychic parameters of subjective tinnitus / Eur Arch Otorhinolaryngol 269:441~447
Calabrese V / 2010 / Oxidative stress, redox homeostasis and cellular stress response in Ménière’s disease: role of vitagenes / Neurochem Res 35:2208~2217
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