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자료유형
학술저널
저자정보
정철기 (조선대학교) 장한 (조선대학교) 이경진 (조선대학교)
저널정보
한국방사선산업학회 방사선산업학회지 방사선산업학회지 제11권 제1호
발행연도
2017.1
수록면
13 - 18 (6page)

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Recently, the number of PET cyclotrons has increased in Korea. A cyclotron mainly produces 18F, which is used for the production of [18F]FDG, a cancer diagnostic radiopharmaceutical. For radiation protection, the discharge control standard under the Nuclear Safety Act limits the radioactive concentration of 18F in the exhaust discharged from a nuclear power utilization facility to below 2,000 Bq m-3. However, the radioactive concentration of 18F discharged during [18F]FDG production at the cyclotron facility at Chosun University is maintained at about 1,500 Bq m-3 on average, which is 75% of the concentration limit of the discharge control standard, and temporarily exceeds the standard as per the real-time monitoring results. This study evaluated the performance of the exhaust filter unit of the cyclotron facility at Chosun University by assessing the concentration of 18F in the exhaust, and an experiment was conducted on the discharge reduction, where 18F is discharged without reacting with the FDG precursors during [18F]FDG synthesis and is immediately captured by the [18F]FDG automatic synthesis unit. Based on the performance evaluation results of the exhaust filter at the cyclotron facility of Chosun University, the measured capture efficiency before and after the filter was found to be 92%. Furthermore, the results of the discharge reduction experiment, where the exhaust 18F was immediately captured by the [18F]FDG synthesizer, showed a very satisfactory 94.3% reduction in the concentration of discharge compared to the existing discharge concentration.

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