지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 124 - 129 (6page)
이용수
초록· 키워드
오류제보하기
Metronidazole is a widely used antibiotic for the treatment of anaerobic bacterial infections. Metronidazole-induced encephalopathy(MIEP) is a rare but potentially reversible disease. The mechanism of MIEP remains unclear, and differences in theneurotoxic effects of oral versus intravenous (IV) metronidazole administration have not yet been determined. We report thecase of a Crohn’s disease (CD) patient who experienced encephalopathy immediately after a single IV dose of metronidazolefollowing long-term exposure to the oral form of the drug. The 64-year-old man with intractable CD experienced a suddenchange in mental status, aphasia, and muscle weakness after IV administration of metronidazole. He had previously taken metronidazoleorally for 13 years and received intermittent IV metronidazole treatments for CD exacerbation. Brain magnetic resonanceimaging (MRI) showed high-intensity signals in the bilateral medial thalamus and the midbrain and pontine tegmentumon fluid-attenuated inversion recovery images. After discontinuation of metronidazole, the high-intensity brain MRI signalsresolved and the patient’s mental status dramatically improved; however, the patient exhibited mild cognitive dysfunction 2months after the onset of encephalopathy.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
김덕환 / 2013 / Clinical Outcomes and Predictive Factors for Response after the First Course of Corticosteroid Therapy in Patients with Crohn’s Disease / Gut and Liver 7(1):58~65
Löfmark S / 2010 / Metronidazole is still the drug of choice for treatment of anaerobic infections / Clin Infect Dis 50(Suppl 1):S16~S23
한동수 / 2014 / Current Status and Prospects of Intestinal Microbiome Studies / Intestinal research 12(3):178~183
김정목 / 2014 / Antimicrobial Proteins in Intestine and Inflammatory Bowel Diseases / Intestinal research 12(1):20~33
Lamp KC / 1999 / Pharmacokinetics and pharmacodynamics of the nitroimidazole antimicrobials / Clin Pharmacokinet 36:353~373
Löfmark S / 2010 / Metronidazole is still the drug of choice for treatment of anaerobic infections / Clin Infect Dis 50(Suppl 1):S16~S23
한동수 / 2014 / Current Status and Prospects of Intestinal Microbiome Studies / Intestinal research 12(3):178~183
김정목 / 2014 / Antimicrobial Proteins in Intestine and Inflammatory Bowel Diseases / Intestinal research 12(1):20~33
Lamp KC / 1999 / Pharmacokinetics and pharmacodynamics of the nitroimidazole antimicrobials / Clin Pharmacokinet 36:353~373
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
A Case of Metronidazole-Induced Encephalopathy: Atypical Involvement of the Brain on MRI
Investigative Magnetic Resonance Imaging
2018 .01
-
Reversible Metronidazole-induced Encephalopathy in a Patient with Acute Lymphoblastic Leukemia during Chemotherapy
Clinical Pediatric Hematology-Oncology
2017 .01
-
Evaluation and Management of Hepatic Encephalopathy: Current Status and Future Directions
Gut and Liver
2016 .01
-
Malignant Posterior Reversible Encephalopathy Syndrome: A Case of Posterior Irreversible Encephalopathy Syndrome
Journal of Clinical Neurology
2016 .01
-
Glyphosate-Induced Encephalopathy: A Case Report
Journal of Clinical Neurology
2019 .01
-
Comparison of the efficacy of amoxicillin-clavulanic acid with metronidazole to azithromycin with metronidazole after surgical removal of impacted lower third molar to prevent infection
대한구강악안면외과학회지
2018 .01
-
Transcriptome profile between brain of hepatic encephalopathy and Alzheimer"s disease
대한체질인류학회 학술대회 연제 초록
2022 .05
-
Early-onset epileptic encephalopathies and the diagnostic approach to underlying causes
Clinical and Experimental Pediatrics
2015 .01
-
Fatal neurological complication after liver transplantation in acute hepatic failure patient with hepatic encephalopathy
고신대학교 의과대학 학술지
2018 .01
-
Uncommon Posterior Reversible Encephalopathy Syndrome in a Sickle-Cell Patient
Journal of Clinical Neurology
2015 .01
-
Surgery in Pediatric Crohn’s Disease: Indications, Timing and Post-Operative Management
Pediatric Gastroenterology, Hepatology & Nutrition
2017 .01
-
Oral Symptoms Related to Vitamin B12 Deficiency in a Patient with Crohn’s Disease
Journal of Oral Medicine and Pain
2018 .12
-
Fatal Encephalopathy Caused by a Urea Cycle Disorder
Journal of Clinical Neurology
2021 .01
-
Posterior Reversible Encephalopathy Syndrome in a Case of Vancomycin-Induced Acute Kidney Injury
Journal of Clinical Neurology
2021 .01
-
Posterior Reversible Encephalopathy Syndrome Related to Carbamazepine-Induced Hypertension
Journal of Clinical Neurology
2020 .01
-
Febrile Hashimoto’s encephalopathy mimicking infectious encephalitis
Annals of Clinical Neurophysiology
2020 .01
-
Chemotherapy for stage IV diseases
대한외과학회 학술대회 초록집
2016 .11
-
Effect of resistance exercise training on Crohn’s disease patients
Intestinal research
2021 .01
-
Korean clinical practice guidelines on biologics for moderate to severe Crohn’s disease
Intestinal research
2023 .01
-
Second Korean guidelines for the management of Crohn’s disease
Intestinal research
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0