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논문 기본 정보

자료유형
학술저널
저자정보
Hye-Sun Kim (Dankook University College of Medicine) 김태진 (단국대학교) 이인호 (제일병원) 홍성란 (단국대학교)
저널정보
대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.27 No.5
발행연도
2016.1
수록면
1 - 11 (11page)

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Objective: This study aimed to examine the meaning and usefulness of sexually transmittedinfection (STI) test when caring for patients who have abnormal cervical cytology and/orpositive high-risk human papillomavirus (HPV) DNA test results. Methods: Among patients who underwent liquid-based cervical cytology and HPV DNAtests at the Obstetrics and Gynecology outpatient clinic, 800 patients who showed abnormalcervical cytology were compared with 200 patients in the control group. Both groups weresimultaneously tested via multiplex real-time polymerase chain reaction for seven types ofSTI-causative microorganisms. Results: The positive rate of high-risk HPV infection in total STIs positive group was 1.47times higher than that of total STIs negative group. The probability of a cytological diagnosisof a grade equal to or higher than atypical squamous cells-cannot exclude high gradesquamous intraepithelial lesion (ASC-H) was significantly higher in patients testing positivefor total STIs (1.46 times), Chlamydia trachomatis (3.21 times), or Mycoplasma genitalicum (3.58times) than in those testing negative. The total STIs positive rate was significantly higher forthose having a cytological diagnosis of a grade equal to or higher than atypical squamouscells of undetermined significance (ASC-US) when high-risk HPV test result was negative. Conclusion: Correlations were present not only between STIs and high-risk HPV infectionbut also between abnormal cervical cytology and STIs. Therefore, additional evaluationof STIs will be helpful to appropriately diagnose and treat patients with abnormal cervicalcytology, positive results on high-risk HPV DNA test, or a cytological diagnosis of ASC-USdespite negative high-risk HPV DNA test result.

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