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논문 기본 정보

자료유형
학술저널
저자정보
이민지 (울산대학교 의과대학 서울아산병원 응급의학과) 김영중 (울산대학교 의과대학 서울아산병원 응급의학과) 안신 (울산대학교) 손창환 (울산대학교) 서동우 (울산대학교) 이재호 (울산대학교) 김원영 (울산대학교 의과대학 서울아산병원 응급의학교실) 임경수 (울산대학교) 이윤선 (울산대학교)
저널정보
대한응급의학회 대한응급의학회지 대한응급의학회지 제27권 제1호
발행연도
2016.1
수록면
15 - 21 (7page)

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Purpose: The purpose of this study is to examine the causes of Pleural effusion (PE) in cancer patients and to compare the clinical characteristics between malignant PE (MPE) and non-MPE. Methods: All consecutive cancer patients with PE who underwent diagnostic thoracentesis from January 1, 2008 to March 31, 2011 were analyzed retrospectively. Results: A total of 719 patients were included; mean age was 58.4±13.6 years and 44.5% were female. The most common cause of PE was MPE (57.7%), followed by parapneumonic or empyema in 16.3%. However, the etiology was significantly different according to primary tumor origin and subtypes of lung cancer. While MPE was most common in lung, breast, and gynecologic cancer, hepatic hydrothorax was the main cause in Hepatocellular carcinoma (HCC). MPE accounted for 85.2% in adenocarcinoma, and 30.2% and 58.8% in squamous cell and small cell carcinomas, respectively. Patients with MPE were younger (57.0 vs. 60.2 years) and female-dominant (55.4% vs. 29.6%) compared to those with non-MPE. MPE had the large size (53.5% vs. 34.9%) and left location of PE (31.3% vs. 19.4%) more frequently than non-MPE, and fewer neutrophils (15.4% vs. 30.6%) and more lymphocytes (32.2% vs. 28.2%), higher levels of pH (7.33 vs. 7.29), and lower levels of glucose (111.5 vs. 129.7 mg/dL) than non-MPE (p<0.001 for all). Conclusion: Overall, MPE was the most common cause of PE in cancer patients. However the etiology of PE was significantly different according to primary tumor origin and subtypes of lung cancer. A difference in age, gender, size and location of PE, cell count, pH, and glucose was observed between MPE and non-MPE.

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