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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 59 - 68 (10page)
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초록· 키워드
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The complement system is a part of the innate immune system that potentiates the ability of antibodies and phagocytic cells to clear microbes and damaged cells. The complement system consists of a number of proteins circulating as inactive precursors. It is stimulated mainly by three pathways: the classical pathway, the alternative pathway, and the lectin pathway. There are many genetic polymorphisms in this system, which can over-activate the immune system. In this study, we collected the polymorphisms reported to over-activate complement cascades that affect the immune system and induce autoimmune diseases.
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참고문헌 (69)
참고문헌 신청
Darbani B / 2015 / Deciphering Mineral Homeostasis in Barley Seed Transfer Cells at Transcriptional Level / PLoS One 10:e0141398
Budding K / 2016 / A Promoter Polymorphism in the CD59 Complement Regulatory Protein Gene in Donor Lungs Correlates With a Higher Risk for Chronic Rejection After Lung Transplantation / Am J Transplant 16:987~998
Krych-Goldberg M / 2001 / Structure-function relationships of complement receptor type 1 / Immunol Rev 180:112~122
Racila DM / 2003 / Homozygous single nucleotide polymorphism of the complement C1QA gene is associated with decreased levels of C1q in patients with subacute cutaneous lupus erythematosus / Lupus 12:124~132
Slingsby JH / 1996 / Homozygous hereditary C1q deficiency and systemic lupus erythematosus. A new family and the molecular basis of C1q deficiency in three families / Arthritis Rheum 39:663~670
Budding K / 2016 / A Promoter Polymorphism in the CD59 Complement Regulatory Protein Gene in Donor Lungs Correlates With a Higher Risk for Chronic Rejection After Lung Transplantation / Am J Transplant 16:987~998
Krych-Goldberg M / 2001 / Structure-function relationships of complement receptor type 1 / Immunol Rev 180:112~122
Racila DM / 2003 / Homozygous single nucleotide polymorphism of the complement C1QA gene is associated with decreased levels of C1q in patients with subacute cutaneous lupus erythematosus / Lupus 12:124~132
Slingsby JH / 1996 / Homozygous hereditary C1q deficiency and systemic lupus erythematosus. A new family and the molecular basis of C1q deficiency in three families / Arthritis Rheum 39:663~670
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