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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 24 - 30 (7page)
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초록· 키워드
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Background: For various reasons, kidney transplant recipients with autosomal dominant polycystic kidney disease (ADPKD) often undergo native nephrectomy in preparation for the transplantation. Simultaneous nephrectomy can result in hypotensive events perioperatively and affect transplant outcome adversely. Our aim was to evaluate the effect of simultaneous native nephrectomy (SNx) on perioperative blood pressure and graft outcome compared to non-nephrectomy (NNx) in renal transplant recipients with ADPKD. Methods: Data regarding renal function and blood pressure were collected from 42 renal transplant recipients with ADPKD. The primary outcome was graft function over 1 year post-transplant. The secondary outcomes were patient and graft survival, postoperative hypotensive events, and blood pressure control. We compared units of anti-hypertensive medication used by transplanted ADPKD patients in the SNx and NNx groups. Results: Patients with SNx during kidney transplantation showed similar rates of patient and graft survival and renal function. Although they had significantly more hypotensive events during the perioperative period (69.2% vs. 37.5% in NNx, P=0.045), no harmful influence on renal function was observed. No difference in mean blood pressure during the 1-year post-transplant period was observed between the two groups; however, the SNx group required fewer units of anti-hypertensive medication. Conclusions: SNx is a relatively safe procedure. Graft outcome in the SNx group was not inferior to that of the NNx group, and patients with SNx can have well-controlled blood pressure.
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등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Goncalves S / 2009 / Autosomal-dominant polycystic kidney disease and kidney transplantation: experience of a single center / Transplant Proc 41:887~890
진동찬 / 2013 / 우리나라 말기신부전 환자의 투석현황 / 대한의사협회지 56(7):562~568
Kirkman MA / 2011 / Native nephrectomy for autosomal dominant polycystic kidney disease: before or after kidney transplantation / BJU Int 108:590~594
Tabibi A / 2005 / Concomitant nephrectomy of massively enlarged kidneys and renal transplantation in autosomal dominant polycystic kidney disease / Transplant Proc 37:2939~2940
Fuller TF / 2005 / End stage polycystic kidney disease: indications and timing of native nephrectomy relative to kidney transplantation / J Urol 174:2284~2288
진동찬 / 2013 / 우리나라 말기신부전 환자의 투석현황 / 대한의사협회지 56(7):562~568
Kirkman MA / 2011 / Native nephrectomy for autosomal dominant polycystic kidney disease: before or after kidney transplantation / BJU Int 108:590~594
Tabibi A / 2005 / Concomitant nephrectomy of massively enlarged kidneys and renal transplantation in autosomal dominant polycystic kidney disease / Transplant Proc 37:2939~2940
Fuller TF / 2005 / End stage polycystic kidney disease: indications and timing of native nephrectomy relative to kidney transplantation / J Urol 174:2284~2288
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