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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 753 - 761 (9page)
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초록· 키워드
오류제보하기
The tumor necrosis factor receptor superfamily (TNFRSF), which includes CD40, LIGHT, and OX40, plays important roles in the initiation and progression of cardiovascular diseases, involving atherosclerosis. CD137, a member of TNFRSF, is a well-known activation-induced T cell co-stimulatory molecule and has been reported to be expressed in human atherosclerotic plaque lesions, and plays pivotal roles in mediating disease processes. In this review, we focus on and summarize recent advances in mouse studies on the involvement of CD137 signaling in the pathogenesis and plaque stability of atherosclerosis, thereby highlighting a valuable therapeutic target in atherosclerosis.
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참고문헌 (90)
참고문헌 신청
Binder CJ / 2002 / Innate and acquired immunity in atherogenesis / Nat Med 8:1218~1226
Steinberg D / 2002 / Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime / Nat Med 8:1211~1217
Hansson GK / 2011 / The immune system in atherosclerosis / Nat Immunol 3:204~212
Hansson GK / 2006 / The immune response in atherosclerosis: a double-edged sword / Nat Rev Immunol 7:508~519
Hansson GK / 2002 / Innate and adaptive immunity in the pathogenesis of atherosclerosis / Circ Res 91:281~291
Steinberg D / 2002 / Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime / Nat Med 8:1211~1217
Hansson GK / 2011 / The immune system in atherosclerosis / Nat Immunol 3:204~212
Hansson GK / 2006 / The immune response in atherosclerosis: a double-edged sword / Nat Rev Immunol 7:508~519
Hansson GK / 2002 / Innate and adaptive immunity in the pathogenesis of atherosclerosis / Circ Res 91:281~291
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