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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 99 - 101 (3page)
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초록· 키워드
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Dabigatran etexilate is one of the new oral anticoagulants approved to reduce the risk of stroke in patients with atrial fibrillation (AF). A variety of bleeding complications with dabigatran have been reported, but reports of hemopericardium are rare. We described a case of a 66 year-old female patient with non-valvular AF receiving dabigatran etexilate 150 mg twice daily for one year who suffered from hemopericardium. Her laboratory tests performed 1 year prior were normal and her admission tests revealed acute renal failure and elevated international normalized ratio (INR) level (4.79). Urgent pericardiocentesis was followed by improved renal functions and normalized INR. Dabigatran etexilate is a new oral anticoagulant that is increasingly used in daily practice. However, life-threatening complications warrant caution. Elevated INR may be related with overdose but the association of bleeding risk of dabigatran and INR requires further confirmation.
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참고문헌 (14)
참고문헌 신청
Wang TJ / 2003 / Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study / Circulation 107:2920~2925
Boehringer Ingelheim Pharmaceuticals Inc / 2011 / Pradaxa (dabigatran etexilate) package insert / Boehringer Ingelheim Pharmaceuticals Inc
Connolly SJ / 2009 / RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation / N Engl J Med 361:1139~1151
Lal Y / 2013 / Dabigatran: a cause of hematologic emergency / Am J Med Sci 346:190~193
Nyby S / 2014 / Fatal bleeding diarrhoea during dabigatran etexilate therapy / Ugeskr Laeger 176:V09140482
Boehringer Ingelheim Pharmaceuticals Inc / 2011 / Pradaxa (dabigatran etexilate) package insert / Boehringer Ingelheim Pharmaceuticals Inc
Connolly SJ / 2009 / RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation / N Engl J Med 361:1139~1151
Lal Y / 2013 / Dabigatran: a cause of hematologic emergency / Am J Med Sci 346:190~193
Nyby S / 2014 / Fatal bleeding diarrhoea during dabigatran etexilate therapy / Ugeskr Laeger 176:V09140482
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